SEED Subsystem: Folate Biosynthesis in Dinoroseobacter shibae DFL-12

Experiments:

Role Gene Name  
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) Dshi_0192
5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) Dshi_2769
5-nucleotidase SurE (EC 3.1.3.5) Dshi_2136
6-pyruvoyl tetrahydrobiopterin synthase (EC 4.2.3.12) No genes
ATPase component of general energizing module of ECF transporters No genes
Alternative Folylglutamate Synthase No genes
Alternative dihydrofolate reductase 2 No genes
Alternative dihydrofolate reductase 3 No genes
Aminodeoxychorismate lyase (EC 4.1.3.38) No genes
COG0488: ATPase components of ABC transporters with duplicated ATPase domains No genes
Dihydrofolate reductase (EC 1.5.1.3) No genes
Dihydrofolate synthase (EC 6.3.2.12) No genes
Dihydroneopterin aldolase (EC 4.1.2.25) Dshi_2399
Dihydroneopterin triphosphate epimerase No genes
Dihydroneopterin triphosphate pyrophosphohydolase Dshi_2915
Dihydroneopterin triphosphate pyrophosphohydolase type 2 No genes
Dihydropteroate synthase (EC 2.5.1.15) Dshi_2398
FolM Alternative dihydrofolate reductase 1 Dshi_0643
Folate biosynthesis protein PTPS-III, catalyzes a reaction that bypasses dihydroneopterin aldolase (FolB) No genes
Folate transporter 3 No genes
Folylpolyglutamate synthase (EC 6.3.2.17) No genes
Formate--tetrahydrofolate ligase (EC 6.3.4.3) Dshi_1283
GTP cyclohydrolase I (EC 3.5.4.16) type 1 No genes
GTP cyclohydrolase I (EC 3.5.4.16) type 2 Dshi_2411
Methionyl-tRNA formyltransferase (EC 2.1.2.9) Dshi_0181
Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) Dshi_1285
Non functional Dihydropteroate synthase 2 No genes
Nucleoside triphosphate pyrophosphohydrolase MazG No genes
Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) Dshi_3925
Para-aminobenzoate synthase, aminase component (EC 2.6.1.85) No genes
PqqC-like protein No genes
Putative DHNTP pyrophosphatase No genes
Related to Dihydropteroate synthase No genes
Serine hydroxymethyltransferase (EC 2.1.2.1) Dshi_0821
  Dshi_2113
Substrate-specific component FolT of folate ECF transporter No genes
Thymidine kinase (EC 2.7.1.21) Dshi_2641
Thymidylate synthase (EC 2.1.1.45) No genes
Thymidylate synthase thyX (EC 2.1.1.-) Dshi_0768
Transaldolase (EC 2.2.1.2) Dshi_1927
Transmembrane component of general energizing module of ECF transporters No genes
Xanthosine/inosine triphosphate pyrophosphatase No genes
alternate gene name: yzbB No genes

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