SEED Subsystem: Valine degradation in Cupriavidus basilensis FW507-4G11

Experiments:

Role Gene Name  
3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) RR42_RS02510
  RR42_RS05760
  RR42_RS10265
  RR42_RS11095
  RR42_RS22630
  RR42_RS28325
  RR42_RS29465
  RR42_RS31050
  RR42_RS35270
3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) RR42_RS24030
  RR42_RS25325
  RR42_RS25640
  RR42_RS28555
3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) RR42_RS28545
Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12) No genes
Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4) RR42_RS21785
  RR42_RS33045
Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4) RR42_RS21785
  RR42_RS33050
Branched-chain amino acid aminotransferase (EC 2.6.1.42) RR42_RS25890
Butyrate kinase (EC 2.7.2.7) No genes
Butyryl-CoA dehydrogenase (EC 1.3.99.2) RR42_RS11345
  RR42_RS13540
  RR42_RS16575
  RR42_RS16795
  RR42_RS21420
  RR42_RS23155
  RR42_RS24795
  RR42_RS24965
  RR42_RS25105
  RR42_RS25970
  RR42_RS28565
  RR42_RS28610
  RR42_RS29500
  RR42_RS31105
  RR42_RS31905
  RR42_RS31910
  RR42_RS31925
  RR42_RS31930
  RR42_RS36460
  RR42_RS36490
Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168) RR42_RS33055
Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase (EC 1.8.1.4) No genes
Enoyl-CoA hydratase (EC 4.2.1.17) RR42_RS00730
  RR42_RS02510
  RR42_RS02525
  RR42_RS03015
  RR42_RS04550
  RR42_RS05755
  RR42_RS10250
  RR42_RS10265
  RR42_RS10270
  RR42_RS11095
  RR42_RS12500
  RR42_RS12795
  RR42_RS13545
  RR42_RS16175
  RR42_RS16790
  RR42_RS18250
  RR42_RS19805
  RR42_RS22630
  RR42_RS22680
  RR42_RS23295
  RR42_RS23450
  RR42_RS23710
  RR42_RS24355
  RR42_RS24895
  RR42_RS25480
  RR42_RS25525
  RR42_RS25900
  RR42_RS28050
  RR42_RS28325
  RR42_RS28330
  RR42_RS29425
  RR42_RS29465
  RR42_RS29940
  RR42_RS29945
  RR42_RS31580
  RR42_RS31935
  RR42_RS31945
  RR42_RS34175
  RR42_RS34180
  RR42_RS34905
  RR42_RS35270
  RR42_RS36495
Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) RR42_RS36335
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.-) No genes
Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) RR42_RS01580
  RR42_RS24025
  RR42_RS25315
  RR42_RS25635
  RR42_RS28560
  RR42_RS34225
Predicted transcriptional regulator of leucine degradation pathway, MerR family No genes
Probable acyl-CoA dehydrogenase (EC 1.3.99.3) RR42_RS24990
  RR42_RS36595
Transcriptional regulator BkdR of isoleucine and valine catabolism operon RR42_RS02930
phosphotransbutyrylase (EC 2.3.1.19) No genes

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