SEED Subsystem: Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate in Cupriavidus basilensis FW507-4G11

Experiments:

Role Gene Name  
Acetaldehyde dehydrogenase (EC 1.2.1.10) No genes
Acetate kinase (EC 2.7.2.1) RR42_RS03800
Acetate permease ActP (cation/acetate symporter) RR42_RS06400
  RR42_RS13875
Acetyl-CoA synthetase (ADP-forming) alpha and beta chains, putative RR42_RS23455
  RR42_RS28040
  RR42_RS31770
  RR42_RS36295
  RR42_RS37035
Acetyl-CoA synthetase (ADP-forming) alpha chain (EC 6.2.1.13) RR42_RS31360
Acetyl-CoA synthetase (ADP-forming) beta chain (EC 6.2.1.13) No genes
Acetyl-coenzyme A synthetase (EC 6.2.1.1) RR42_RS06210
  RR42_RS10650
  RR42_RS13880
  RR42_RS24890
  RR42_RS29035
Acetyltransferase AcuA, acetyl-CoA synthetase inhibitor No genes
Acylphosphate phosphohydrolase (EC 3.6.1.7), putative RR42_RS18325
Aldehyde dehydrogenase (EC 1.2.1.3) RR42_RS04280
  RR42_RS11360
  RR42_RS13660
  RR42_RS21485
  RR42_RS24065
  RR42_RS24390
  RR42_RS24840
  RR42_RS25005
  RR42_RS25010
  RR42_RS26255
  RR42_RS27780
  RR42_RS29955
  RR42_RS32140
  RR42_RS34255
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) RR42_RS07370
  RR42_RS21775
  RR42_RS26120
Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex (EC 1.8.1.4) RR42_RS07380
  RR42_RS21770
  RR42_RS26115
Lactate 2-monooxygenase (EC 1.13.12.4) No genes
NAD-dependent protein deacetylase of SIR2 family RR42_RS13055
  RR42_RS27705
NAD-independent protein deacetylase AcuC No genes
Phosphate acetyltransferase (EC 2.3.1.8) RR42_RS03805
  RR42_RS33690
Protein acetyltransferase RR42_RS01345
  RR42_RS09770
Putative membrane protein, clustering with ActP RR42_RS06405
Pyruvate decarboxylase (EC 4.1.1.1) No genes
Pyruvate dehydrogenase E1 component (EC 1.2.4.1) RR42_RS07365
  RR42_RS24415
  RR42_RS26125
  RR42_RS29920
  RR42_RS32980
  RR42_RS34220
Pyruvate dehydrogenase E1 component alpha subunit (EC 1.2.4.1) No genes
Pyruvate dehydrogenase E1 component beta subunit (EC 1.2.4.1) No genes
Pyruvate oxidase (EC 1.2.3.3) No genes
Pyruvate oxidase [ubiquinone, cytochrome] (EC 1.2.2.2) No genes

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