SEED Subsystem: Proline, 4-hydroxyproline uptake and utilization in Cupriavidus basilensis FW507-4G11

Experiments:

Role Gene Name  
1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) RR42_RS36370
4-hydroxyproline epimerase (EC 5.1.1.8) RR42_RS36345
Aldehyde dehydrogenase (EC 1.2.1.3) in 4-hydroxyproline catabolic gene cluster No genes
Amino acid permease in 4-hydroxyproline catabolic gene cluster No genes
D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster No genes
D-amino-acid oxidase (EC 1.4.3.3) RR42_RS36350
D-proline reductase, 23 kDa subunit (EC 1.21.4.1) No genes
D-proline reductase, 26 kDa subunit (EC 1.21.4.1) No genes
D-proline reductase, 45 kDa subunit (EC 1.21.4.1) No genes
Delta 1-pyrroline-5-carboxylate dehydrogenase domain protein No genes
Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) RR42_RS20125
Dipeptidyl peptidase IV in 4-hydroxyproline catabolic gene cluster No genes
Hypothetical, similar to sarcosine oxidase alpha subunit, 2Fe-2S domain RR42_RS36355
Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) RR42_RS04830
  RR42_RS23090
L-Proline/Glycine betaine transporter ProP RR42_RS26230
  RR42_RS27720
  RR42_RS29835
  RR42_RS30080
  RR42_RS30215
  RR42_RS32465
  RR42_RS35030
Microbial collagenase, secreted (EC 3.4.24.3) No genes
Not a Proline racemase, nor 4-hydroxyproline epimerase [missing catalytic residues] No genes
Predicted 4-hydroxyproline dipeptidase No genes
Predicted regulator PutR for proline utilization, GntR family RR42_RS19410
  RR42_RS30405
  RR42_RS31395
ProQ: influences osmotic activation of compatible solute ProP No genes
Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase) RR42_RS20125
Proline iminopeptidase (EC 3.4.11.5) RR42_RS11455
  RR42_RS16705
Proline racemase (EC 5.1.1.4) No genes
Proline-specific permease proY No genes
Proline/sodium symporter PutP (TC 2.A.21.2.1) No genes
PutR, transcriptional activator of PutA and PutP No genes
Putative beta-galactosidase in 4-hydroxyproline catabolic gene cluster No genes
Putative oxidoreductase in 4-hydroxyproline catabolic gene cluster RR42_RS36360
Similar to eukaryotic Peptidyl prolyl 4-hydroxylase, alpha subunit (EC 1.14.11.2) RR42_RS17915
Transcriptional repressor of PutA and PutP RR42_RS20125
Ureidoglycolate/malate/sulfolactate dehydrogenase family (EC 1.1.1.-) No genes
putPA fragment of control region No genes

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