SEED Subsystem: Leucine Degradation and HMG-CoA Metabolism in Cupriavidus basilensis FW507-4G11

Role	Gene	Name
Acetoacetyl-CoA synthetase (EC 6.2.1.16)	RR42_RS10085
	RR42_RS15595
	RR42_RS26915
	RR42_RS29475
	RR42_RS36095
Acetoacetyl-CoA synthetase [leucine] (EC 6.2.1.16)	RR42_RS16170
	RR42_RS16600
	RR42_RS18150
Biotin carboxyl carrier protein of methylcrotonyl-CoA carboxylase	No genes
Biotin carboxylase of methylcrotonyl-CoA carboxylase (EC 6.3.4.14)	RR42_RS01350
Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12)	No genes
Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4)	RR42_RS21785
	RR42_RS33045
Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4)	RR42_RS21785
	RR42_RS33050
Branched-chain amino acid aminotransferase (EC 2.6.1.42)	RR42_RS25890
Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168)	RR42_RS33055
Dihydrolipoamide dehydrogenase (EC 1.8.1.4)	RR42_RS34380
Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase (EC 1.8.1.4)	No genes
Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)	RR42_RS00955
	RR42_RS12420
	RR42_RS12425
	RR42_RS13255
	RR42_RS25095
	RR42_RS25280
	RR42_RS25285
Hydroxymethylglutaryl-CoA reductase (EC 1.1.1.34)	No genes
Hydroxymethylglutaryl-CoA synthase (EC 2.3.3.10)	No genes
Isovaleryl-CoA dehydrogenase (EC 1.3.99.10)	No genes
Leucine dehydrogenase (EC 1.4.1.9)	RR42_RS10345
	RR42_RS22850
Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)	RR42_RS26895
	RR42_RS29420
	RR42_RS32735
Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)	RR42_RS26905
	RR42_RS29410
Methylglutaconyl-CoA hydratase (EC 4.2.1.18)	RR42_RS26900
Predicted transcriptional regulator of leucine degradation pathway, MerR family	No genes
Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5)	RR42_RS06555
Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (EC 2.8.3.5)	RR42_RS06560