SEED Subsystem: Folate Biosynthesis in Ralstonia sp. UNC404CL21Col

Experiments:

Role Gene Name  
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) ABZR87_RS00940
5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) ABZR87_RS04880
5-nucleotidase SurE (EC 3.1.3.5) ABZR87_RS10860
6-pyruvoyl tetrahydrobiopterin synthase (EC 4.2.3.12) No genes
ATPase component of general energizing module of ECF transporters No genes
Alternative Folylglutamate Synthase No genes
Alternative dihydrofolate reductase 2 No genes
Alternative dihydrofolate reductase 3 ABZR87_RS08035
Aminodeoxychorismate lyase (EC 4.1.3.38) ABZR87_RS00965
COG0488: ATPase components of ABC transporters with duplicated ATPase domains ABZR87_RS09735
Dihydrofolate reductase (EC 1.5.1.3) ABZR87_RS09665
  ABZR87_RS22850
Dihydrofolate synthase (EC 6.3.2.12) ABZR87_RS14480
Dihydroneopterin aldolase (EC 4.1.2.25) ABZR87_RS05650
Dihydroneopterin triphosphate epimerase No genes
Dihydroneopterin triphosphate pyrophosphohydolase No genes
Dihydroneopterin triphosphate pyrophosphohydolase type 2 ABZR87_RS07450
Dihydropteroate synthase (EC 2.5.1.15) ABZR87_RS14110
FolM Alternative dihydrofolate reductase 1 ABZR87_RS05645
Folate biosynthesis protein PTPS-III, catalyzes a reaction that bypasses dihydroneopterin aldolase (FolB) No genes
Folate transporter 3 No genes
Folylpolyglutamate synthase (EC 6.3.2.17) ABZR87_RS14480
Formate--tetrahydrofolate ligase (EC 6.3.4.3) No genes
GTP cyclohydrolase I (EC 3.5.4.16) type 1 ABZR87_RS21070
GTP cyclohydrolase I (EC 3.5.4.16) type 2 ABZR87_RS15630
Methionyl-tRNA formyltransferase (EC 2.1.2.9) ABZR87_RS04965
Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) ABZR87_RS13485
Non functional Dihydropteroate synthase 2 No genes
Nucleoside triphosphate pyrophosphohydrolase MazG No genes
Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) No genes
Para-aminobenzoate synthase, aminase component (EC 2.6.1.85) ABZR87_RS00965
PqqC-like protein No genes
Putative DHNTP pyrophosphatase No genes
Related to Dihydropteroate synthase No genes
Serine hydroxymethyltransferase (EC 2.1.2.1) ABZR87_RS08955
Substrate-specific component FolT of folate ECF transporter No genes
Thymidine kinase (EC 2.7.1.21) No genes
Thymidylate synthase (EC 2.1.1.45) ABZR87_RS09670
Thymidylate synthase thyX (EC 2.1.1.-) No genes
Transaldolase (EC 2.2.1.2) ABZR87_RS11000
Transmembrane component of general energizing module of ECF transporters No genes
Xanthosine/inosine triphosphate pyrophosphatase No genes
alternate gene name: yzbB No genes

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