SEED Subsystem: Folate Biosynthesis in Phocaeicola vulgatus CL09T03C04

Experiments:

Role Gene Name  
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) HMPREF1058_RS03875
  HMPREF1058_RS11325
5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) HMPREF1058_RS17145
5-nucleotidase SurE (EC 3.1.3.5) HMPREF1058_RS14085
6-pyruvoyl tetrahydrobiopterin synthase (EC 4.2.3.12) No genes
ATPase component of general energizing module of ECF transporters No genes
Alternative Folylglutamate Synthase No genes
Alternative dihydrofolate reductase 2 No genes
Alternative dihydrofolate reductase 3 No genes
Aminodeoxychorismate lyase (EC 4.1.3.38) HMPREF1058_RS15210
COG0488: ATPase components of ABC transporters with duplicated ATPase domains HMPREF1058_RS18425
Dihydrofolate reductase (EC 1.5.1.3) HMPREF1058_RS14275
Dihydrofolate synthase (EC 6.3.2.12) HMPREF1058_RS15675
Dihydroneopterin aldolase (EC 4.1.2.25) HMPREF1058_RS07600
Dihydroneopterin triphosphate epimerase No genes
Dihydroneopterin triphosphate pyrophosphohydolase No genes
Dihydroneopterin triphosphate pyrophosphohydolase type 2 No genes
Dihydropteroate synthase (EC 2.5.1.15) HMPREF1058_RS08475
FolM Alternative dihydrofolate reductase 1 No genes
Folate biosynthesis protein PTPS-III, catalyzes a reaction that bypasses dihydroneopterin aldolase (FolB) No genes
Folate transporter 3 No genes
Folylpolyglutamate synthase (EC 6.3.2.17) HMPREF1058_RS15675
Formate--tetrahydrofolate ligase (EC 6.3.4.3) HMPREF1058_RS18765
GTP cyclohydrolase I (EC 3.5.4.16) type 1 HMPREF1058_RS08260
GTP cyclohydrolase I (EC 3.5.4.16) type 2 No genes
Methionyl-tRNA formyltransferase (EC 2.1.2.9) HMPREF1058_RS07730
Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) HMPREF1058_RS15075
Non functional Dihydropteroate synthase 2 No genes
Nucleoside triphosphate pyrophosphohydrolase MazG No genes
Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) No genes
Para-aminobenzoate synthase, aminase component (EC 2.6.1.85) HMPREF1058_RS15205
PqqC-like protein No genes
Putative DHNTP pyrophosphatase No genes
Related to Dihydropteroate synthase No genes
Serine hydroxymethyltransferase (EC 2.1.2.1) HMPREF1058_RS03800
Substrate-specific component FolT of folate ECF transporter No genes
Thymidine kinase (EC 2.7.1.21) HMPREF1058_RS13725
Thymidylate synthase (EC 2.1.1.45) HMPREF1058_RS14280
Thymidylate synthase thyX (EC 2.1.1.-) No genes
Transaldolase (EC 2.2.1.2) HMPREF1058_RS03840
Transmembrane component of general energizing module of ECF transporters No genes
Xanthosine/inosine triphosphate pyrophosphatase No genes
alternate gene name: yzbB HMPREF1058_RS07460

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