SEED Subsystem: Folate Biosynthesis in Paraburkholderia bryophila 376MFSha3.1

Experiments:

Role Gene Name  
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) H281DRAFT_04705
5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) H281DRAFT_05815
5-nucleotidase SurE (EC 3.1.3.5) H281DRAFT_00840
6-pyruvoyl tetrahydrobiopterin synthase (EC 4.2.3.12) No genes
ATPase component of general energizing module of ECF transporters No genes
Alternative Folylglutamate Synthase No genes
Alternative dihydrofolate reductase 2 No genes
Alternative dihydrofolate reductase 3 H281DRAFT_04196
Aminodeoxychorismate lyase (EC 4.1.3.38) H281DRAFT_04702
COG0488: ATPase components of ABC transporters with duplicated ATPase domains H281DRAFT_00263
Dihydrofolate reductase (EC 1.5.1.3) H281DRAFT_04305
Dihydrofolate synthase (EC 6.3.2.12) H281DRAFT_06063
Dihydroneopterin aldolase (EC 4.1.2.25) H281DRAFT_01306
  H281DRAFT_05823
Dihydroneopterin triphosphate epimerase No genes
Dihydroneopterin triphosphate pyrophosphohydolase No genes
Dihydroneopterin triphosphate pyrophosphohydolase type 2 H281DRAFT_04621
Dihydropteroate synthase (EC 2.5.1.15) H281DRAFT_04409
FolM Alternative dihydrofolate reductase 1 H281DRAFT_05822
Folate biosynthesis protein PTPS-III, catalyzes a reaction that bypasses dihydroneopterin aldolase (FolB) No genes
Folate transporter 3 No genes
Folylpolyglutamate synthase (EC 6.3.2.17) H281DRAFT_06063
Formate--tetrahydrofolate ligase (EC 6.3.4.3) No genes
GTP cyclohydrolase I (EC 3.5.4.16) type 1 H281DRAFT_01599
GTP cyclohydrolase I (EC 3.5.4.16) type 2 H281DRAFT_06014
Methionyl-tRNA formyltransferase (EC 2.1.2.9) H281DRAFT_02240
Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) H281DRAFT_00463
Non functional Dihydropteroate synthase 2 No genes
Nucleoside triphosphate pyrophosphohydrolase MazG No genes
Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) H281DRAFT_03954
Para-aminobenzoate synthase, aminase component (EC 2.6.1.85) H281DRAFT_04702
PqqC-like protein No genes
Putative DHNTP pyrophosphatase No genes
Related to Dihydropteroate synthase H281DRAFT_01309
Serine hydroxymethyltransferase (EC 2.1.2.1) H281DRAFT_00990
  H281DRAFT_02468
  H281DRAFT_04726
Substrate-specific component FolT of folate ECF transporter No genes
Thymidine kinase (EC 2.7.1.21) No genes
Thymidylate synthase (EC 2.1.1.45) H281DRAFT_04307
Thymidylate synthase thyX (EC 2.1.1.-) No genes
Transaldolase (EC 2.2.1.2) H281DRAFT_00286
Transmembrane component of general energizing module of ECF transporters No genes
Xanthosine/inosine triphosphate pyrophosphatase No genes
alternate gene name: yzbB No genes

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