SEED Subsystem: Glycine and Serine Utilization in Bacteroides thetaiotaomicron VPI-5482

Experiments:

Role Gene Name BHIS with Trimethoprim 0.00625 mM  
⨯
2-amino-3-ketobutyrate coenzyme A ligase (EC 2.3.1.29) BT1371 -0.2
Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10) BT4584 +0.2
Cystathionine beta-synthase (EC 4.2.1.22) No genes
Cystathionine gamma-lyase (EC 4.4.1.1) No genes
D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) BT1152 +0.8
  BT1207 +0.1
D-serine dehydratase (EC 4.3.1.18) No genes
D-serine dehydratase transcriptional activator No genes
D-serine permease DsdX No genes
D-serine/D-alanine/glycine transporter No genes
Glycerate kinase (EC 2.7.1.31) BT1437 +0.7
Glycine cleavage system H protein BT2519 -1.1
Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) BT1147 +0.4
Glycine dehydrogenase [decarboxylating] (glycine cleavage system P1 protein) (EC 1.4.4.2) No genes
Glycine dehydrogenase [decarboxylating] (glycine cleavage system P2 protein) (EC 1.4.4.2) No genes
L-serine dehydratase (EC 4.3.1.17) No genes
L-serine dehydratase 1 (EC 4.3.1.17) No genes
L-serine dehydratase, alpha subunit (EC 4.3.1.17) BT4678 -2.3
L-serine dehydratase, beta subunit (EC 4.3.1.17) BT4678 -2.3
Monoamine oxidase (1.4.3.4) No genes
Phosphoserine aminotransferase (EC 2.6.1.52) BT1153 -0.7
Phosphoserine phosphatase (EC 3.1.3.3) BT0832 +0.0
Serine hydroxymethyltransferase (EC 2.1.2.1) BT0738 +0.8
Serine transporter No genes
Seryl-tRNA synthetase (EC 6.1.1.11) BT4312 N.D.
Threonine dehydratase, catabolic (EC 4.3.1.19) No genes

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