SEED Subsystem: Folate Biosynthesis in Burkholderia phytofirmans PsJN

Experiments:

Role Gene Name Deoxyribonucleic from herring sperm 10 mg/mL (C)  
⨯
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) BPHYT_RS03615 N.D.
5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) BPHYT_RS18615 -0.2
5-nucleotidase SurE (EC 3.1.3.5) BPHYT_RS09100 +0.0
  BPHYT_RS26570 +0.2
6-pyruvoyl tetrahydrobiopterin synthase (EC 4.2.3.12) No genes
ATPase component of general energizing module of ECF transporters No genes
Alternative Folylglutamate Synthase No genes
Alternative dihydrofolate reductase 2 No genes
Alternative dihydrofolate reductase 3 BPHYT_RS16300 -1.8
Aminodeoxychorismate lyase (EC 4.1.3.38) BPHYT_RS03600 -0.2
COG0488: ATPase components of ABC transporters with duplicated ATPase domains BPHYT_RS05925 -0.8
Dihydrofolate reductase (EC 1.5.1.3) BPHYT_RS06365 +0.1
  BPHYT_RS14700 N.D.
Dihydrofolate synthase (EC 6.3.2.12) No genes
Dihydroneopterin aldolase (EC 4.1.2.25) BPHYT_RS18575 N.D.
Dihydroneopterin triphosphate epimerase No genes
Dihydroneopterin triphosphate pyrophosphohydolase No genes
Dihydroneopterin triphosphate pyrophosphohydolase type 2 BPHYT_RS03205 -0.2
Dihydropteroate synthase (EC 2.5.1.15) BPHYT_RS14160 N.D.
FolM Alternative dihydrofolate reductase 1 BPHYT_RS18580 +0.8
Folate biosynthesis protein PTPS-III, catalyzes a reaction that bypasses dihydroneopterin aldolase (FolB) No genes
Folate transporter 3 No genes
Folylpolyglutamate synthase (EC 6.3.2.17) No genes
Formate--tetrahydrofolate ligase (EC 6.3.4.3) No genes
GTP cyclohydrolase I (EC 3.5.4.16) type 1 BPHYT_RS21405 +0.2
GTP cyclohydrolase I (EC 3.5.4.16) type 2 BPHYT_RS33570 +0.4
Methionyl-tRNA formyltransferase (EC 2.1.2.9) BPHYT_RS01460 N.D.
Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) BPHYT_RS12865 N.D.
Non functional Dihydropteroate synthase 2 No genes
Nucleoside triphosphate pyrophosphohydrolase MazG No genes
Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) BPHYT_RS15045 +0.2
Para-aminobenzoate synthase, aminase component (EC 2.6.1.85) BPHYT_RS03600 -0.2
PqqC-like protein No genes
Putative DHNTP pyrophosphatase No genes
Related to Dihydropteroate synthase No genes
Serine hydroxymethyltransferase (EC 2.1.2.1) BPHYT_RS01260 -0.1
  BPHYT_RS03725 -1.9
  BPHYT_RS25180 -0.3
Substrate-specific component FolT of folate ECF transporter No genes
Thymidine kinase (EC 2.7.1.21) No genes
Thymidylate synthase (EC 2.1.1.45) BPHYT_RS14650 N.D.
Thymidylate synthase thyX (EC 2.1.1.-) No genes
Transaldolase (EC 2.2.1.2) BPHYT_RS06045 +0.3
Transmembrane component of general energizing module of ECF transporters No genes
Xanthosine/inosine triphosphate pyrophosphatase No genes
alternate gene name: yzbB BPHYT_RS27845 +0.2

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