SEED Subsystem: Heme and Siroheme Biosynthesis in Desulfovibrio vulgaris Hildenborough JW710

Experiments:

Role Gene Name MoLS4 with L-Glycine (N)  
5-aminolevulinate synthase (EC 2.3.1.37) No genes
Coproporphyrinogen III oxidase, aerobic (EC 1.3.3.3) No genes
Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) No genes
Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22), divergent, putative DVU3057 -0.1
Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22), divergent, putative 2 No genes
Distant homolog of E. coli HemX protein in Xanthomonadaceae No genes
Ferrochelatase, protoheme ferro-lyase (EC 4.99.1.1) No genes
Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8) DVU3168 hemL N.D.
Glutamyl-tRNA reductase (EC 1.2.1.70) DVU1461 hemA N.D.
Glutamyl-tRNA synthetase (EC 6.1.1.17) DVU2552 gltX-2 N.D.
HemX protein, negative effector of steady-state concentration of glutamyl-tRNA reductase DVU1462 -1.8
Hemoprotein HemQ, essential component of heme biosynthetic pathway in Gram-positive bacteria No genes
Hypothetical membrane protein, possible involvement in cytochrome functioning/assembly No genes
Hypothetical radical SAM family enzyme, NOT coproporphyrinogen III oxidase, oxygen-independent No genes
Porphobilinogen deaminase (EC 2.5.1.61) DVU1890 hemC N.D.
Porphobilinogen synthase (EC 4.2.1.24) DVU0856 hemB N.D.
Precorrin-2 oxidase (EC 1.3.1.76) DVU1463 cysG-1 N.D.
Protoporphyrinogen IX oxidase, aerobic (EC 1.3.3.4) No genes
Protoporphyrinogen IX oxidase, oxygen-independent, HemG (EC 1.3.-.-) No genes
Putative coproporphyrinogen III oxidase of BS HemN-type, oxygen-independent (EC 1.3.99.22), in heat shock gene cluster No genes
Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB No genes
Radical SAM family protein HutW, similar to coproporphyrinogen III oxidase, oxygen-independent, associated with heme uptake No genes
Sirohydrochlorin ferrochelatase (EC 4.99.1.4) DVU0650 -2.0
  DVU1365 N.D.
Uroporphyrinogen III decarboxylase (EC 4.1.1.37) No genes
Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) DVU0734 cysG-1 N.D.
Uroporphyrinogen-III synthase (EC 4.2.1.75) DVU0734 cysG-1 N.D.
Uroporphyrinogen-III synthase, divergent, Flavobacterial type (EC 4.2.1.75) No genes
Uroporphyrinogen-III synthase, divergent, Francisella type (EC 4.2.1.75) No genes

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