SEED Subsystem: Folate Biosynthesis in Pseudomonas syringae pv. syringae B728a

Experiments:

Role Gene Name 4-hydroxybutyric (C)  
⨯
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) Psyr_0829 N.D.
  Psyr_4635 N.D.
5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) Psyr_0317 -3.4
5-nucleotidase SurE (EC 3.1.3.5) No genes
6-pyruvoyl tetrahydrobiopterin synthase (EC 4.2.3.12) No genes
ATPase component of general energizing module of ECF transporters No genes
Alternative Folylglutamate Synthase No genes
Alternative dihydrofolate reductase 2 No genes
Alternative dihydrofolate reductase 3 No genes
Aminodeoxychorismate lyase (EC 4.1.3.38) Psyr_1650 +0.2
COG0488: ATPase components of ABC transporters with duplicated ATPase domains Psyr_3294 +0.1
Dihydrofolate reductase (EC 1.5.1.3) Psyr_4737 N.D.
Dihydrofolate synthase (EC 6.3.2.12) No genes
Dihydroneopterin aldolase (EC 4.1.2.25) Psyr_4636 N.D.
Dihydroneopterin triphosphate epimerase Psyr_1019 +0.7
Dihydroneopterin triphosphate pyrophosphohydolase No genes
Dihydroneopterin triphosphate pyrophosphohydolase type 2 No genes
Dihydropteroate synthase (EC 2.5.1.15) Psyr_4186 N.D.
FolM Alternative dihydrofolate reductase 1 Psyr_1021 -0.7
Folate biosynthesis protein PTPS-III, catalyzes a reaction that bypasses dihydroneopterin aldolase (FolB) No genes
Folate transporter 3 No genes
Folylpolyglutamate synthase (EC 6.3.2.17) No genes
Formate--tetrahydrofolate ligase (EC 6.3.4.3) No genes
GTP cyclohydrolase I (EC 3.5.4.16) type 1 Psyr_1020 -0.1
  Psyr_1845 -0.4
GTP cyclohydrolase I (EC 3.5.4.16) type 2 Psyr_2269 -0.3
Methionyl-tRNA formyltransferase (EC 2.1.2.9) Psyr_0018 N.D.
Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) Psyr_1743 N.D.
  Psyr_2225 -0.1
Non functional Dihydropteroate synthase 2 No genes
Nucleoside triphosphate pyrophosphohydrolase MazG No genes
Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) No genes
Para-aminobenzoate synthase, aminase component (EC 2.6.1.85) Psyr_2080 -0.0
PqqC-like protein No genes
Putative DHNTP pyrophosphatase No genes
Related to Dihydropteroate synthase No genes
Serine hydroxymethyltransferase (EC 2.1.2.1) Psyr_4270 -3.6
  Psyr_4712 +0.0
Substrate-specific component FolT of folate ECF transporter No genes
Thymidine kinase (EC 2.7.1.21) No genes
Thymidylate synthase (EC 2.1.1.45) Psyr_4840 N.D.
Thymidylate synthase thyX (EC 2.1.1.-) No genes
Transaldolase (EC 2.2.1.2) Psyr_1914 -3.5
Transmembrane component of general energizing module of ECF transporters No genes
Xanthosine/inosine triphosphate pyrophosphatase No genes
alternate gene name: yzbB No genes

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