SEED Subsystem: Arginine and Ornithine Degradation in Klebsiella michiganensis M5al

Experiments:

Role Gene Name Cobalt chloride 0.5 mM  
Agmatinase (EC 3.5.3.11) BWI76_RS21880 +0.1
  BWI76_RS21925 -0.4
  BWI76_RS24025 +2.7
Agmatine deiminase (EC 3.5.3.12) No genes
Arginase (EC 3.5.3.1) No genes
Arginine ABC transporter, ATP-binding protein ArtP BWI76_RS09520 +0.2
Arginine ABC transporter, periplasmic arginine-binding protein ArtI BWI76_RS02485 +0.1
  BWI76_RS09515 -1.2
Arginine ABC transporter, periplasmic arginine-binding protein ArtJ BWI76_RS09500 -0.3
  BWI76_RS21895 +0.2
Arginine ABC transporter, permease protein ArtM BWI76_RS09505 +0.9
Arginine ABC transporter, permease protein ArtQ BWI76_RS09510 N.D.
Arginine N-succinyltransferase (EC 2.3.1.109) BWI76_RS11675 -0.1
Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) No genes
Arginine N-succinyltransferase, beta subunit (EC 2.3.1.109) No genes
Arginine decarboxylase (EC 4.1.1.19) No genes
Arginine decarboxylase, catabolic (EC 4.1.1.19) No genes
Arginine deiminase (EC 3.5.3.6) No genes
Arginine pathway regulatory protein ArgR, repressor of arg regulon BWI76_RS25425 +1.8
Arginine permease RocE No genes
Arginine utilization protein RocB No genes
Arginine utilization regulatory protein RocR No genes
Arginine/agmatine antiporter No genes
Arginine/ornithine ABC transporter, ATP-binding protein AotP No genes
Arginine/ornithine ABC transporter, periplasmic arginine/ornithine binding protein No genes
Arginine/ornithine ABC transporter, permease protein AotM No genes
Arginine/ornithine ABC transporter, permease protein AotQ No genes
Arginine/ornithine antiporter ArcD BWI76_RS16225 +0.8
Biosynthetic arginine decarboxylase (EC 4.1.1.19) BWI76_RS24030 +2.3
Carbamate kinase (EC 2.7.2.2) BWI76_RS07060 -0.1
  BWI76_RS17520 -0.3
Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) BWI76_RS10795 +0.6
Histidine ABC transporter, ATP-binding protein HisP (TC 3.A.1.3.1) BWI76_RS20320 -0.2
Histidine ABC transporter, histidine-binding periplasmic protein precursor HisJ (TC 3.A.1.3.1) BWI76_RS07345 +0.1
  BWI76_RS14410 +0.6
  BWI76_RS19240 -0.4
  BWI76_RS20335 +0.1
Histidine ABC transporter, permease protein HisM (TC 3.A.1.3.1) BWI76_RS19230 -0.7
  BWI76_RS20325 +0.0
Histidine ABC transporter, permease protein HisQ (TC 3.A.1.3.1) BWI76_RS19235 -0.1
  BWI76_RS20330 +0.2
Lysine-arginine-ornithine-binding periplasmic protein precursor (TC 3.A.1.3.1) BWI76_RS10285 +0.0
  BWI76_RS20340 -0.0
N-carbamoylputrescine amidase (3.5.1.53) No genes
NADP-specific glutamate dehydrogenase (EC 1.4.1.4) BWI76_RS11610 +0.1
Ornithine aminotransferase (EC 2.6.1.13) No genes
Ornithine carbamoyltransferase (EC 2.1.3.3) BWI76_RS03010 -0.4
Ornithine cyclodeaminase (EC 4.3.1.12) No genes
Ornithine decarboxylase (EC 4.1.1.17) BWI76_RS24175 -0.0
Putrescine aminotransferase (EC 2.6.1.82) BWI76_RS24630 -0.4
Succinylarginine dihydrolase (EC 3.5.3.23) BWI76_RS11685 -0.1
Succinylglutamate desuccinylase (EC 3.5.1.96) BWI76_RS11690 -0.6
Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) BWI76_RS11680 -0.3
Succinylornithine transaminase (EC 2.6.1.81) BWI76_RS11670 -0.1
Transcriptional regulator ArcR essential for anaerobic expression of the ADI pathway, Crp/Fnr family No genes
Transcriptional regulator of catabolic arginine decarboxylase (adiA) No genes

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