SEED Subsystem: DNA-replication in Bacteroides thetaiotaomicron VPI-5482

Experiments:

Role Gene Name BHIS with Dimetridazole 0.025 mM  
⨯
ATP-dependent DNA helicase RecG (EC 3.6.1.-) BT3924 N.D.
ATP-dependent DNA helicase RecQ BT1848 -0.3
  BT3844 N.D.
Arrested fork binding No genes
Chromosomal replication initiator protein DnaA BT2143 N.D.
Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) BT_1664 ruvC N.D.
DNA polymerase I (EC 2.7.7.7) BT3260 -3.2
DNA polymerase II (EC 2.7.7.7) No genes
DNA polymerase III alpha subunit (EC 2.7.7.7) BT2230 N.D.
DNA polymerase III beta subunit (EC 2.7.7.7) BT1364 N.D.
DNA polymerase III chi subunit (EC 2.7.7.7) No genes
DNA polymerase III delta prime subunit (EC 2.7.7.7) BT3820 N.D.
DNA polymerase III delta subunit (EC 2.7.7.7) BT0889 N.D.
DNA polymerase III epsilon subunit (EC 2.7.7.7) BT1431 -0.0
DNA polymerase III psi subunit (EC 2.7.7.7) No genes
DNA polymerase III subunits gamma and tau (EC 2.7.7.7) BT1610 N.D.
DNA polymerase III theta subunit (EC 2.7.7.7) No genes
DNA primase (EC 2.7.7.-) BT1127 +0.1
  BT3932 N.D.
DNA primase (EC 2.7.7.-), phage-associated No genes
DNA primase TraC (EC 2.7.7.-) No genes
DNA repair protein RecN BT1361 -3.2
DNA replication protein DnaC No genes
DNA replication terminus site-binding protein No genes
Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) No genes
Exodeoxyribonuclease V beta chain (EC 3.1.11.5) No genes
Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) No genes
Helicase PriA essential for oriC/DnaA-independent DNA replication BT2752 N.D.
Helicase loader DnaI No genes
Holliday junction DNA helicase RuvA BT1978 N.D.
Holliday junction DNA helicase RuvB BT3285 N.D.
Primosomal protein I No genes
Primosomal replication protein N No genes
Primosomal replication protein N prime prime No genes
RecA protein BT4610 -3.2
Recombination protein RecR BT1081 -2.5
Replicative DNA helicase (EC 3.6.1.-) BT0625 N.D.
  BT1516 +0.3
Replicative DNA helicase (EC 3.6.1.-) [SA14-24] No genes
Single-stranded-DNA-specific exonuclease RecJ (EC 3.1.-.-) BT3939 N.D.
Transcription-repair coupling factor BT0252 -1.6

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