SEED Subsystem: Cysteine Biosynthesis in Klebsiella michiganensis M5al

Experiments:

Role Gene Name D,L-Malic Acid (C)  
⨯
Adenylylsulfate kinase (EC 2.7.1.25) BWI76_RS22690 -4.1
Cys regulon transcriptional activator CysB BWI76_RS11930 N.D.
Cystathionine beta-synthase (EC 4.2.1.22) BWI76_RS24205 -0.2
Cystathionine gamma-lyase (EC 4.4.1.1) BWI76_RS24210 +0.0
Cysteine synthase (EC 2.5.1.47) BWI76_RS20640 -3.2
Cysteine synthase A (EC 2.5.1.47) No genes
Cysteine synthase B (EC 2.5.1.47) BWI76_RS06575 +0.1
  BWI76_RS20685 N.D.
Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) BWI76_RS22755 -4.8
Serine acetyltransferase (EC 2.3.1.30) BWI76_RS05560 N.D.
  BWI76_RS27205 N.D.
Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) BWI76_RS22695 -3.1
Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) BWI76_RS22700 -3.7
Sulfate and thiosulfate binding protein CysP BWI76_RS20705 -1.3
Sulfate and thiosulfate import ATP-binding protein CysA (EC 3.6.3.25) BWI76_RS20690 -1.4
Sulfate permease BWI76_RS19875 N.D.
  BWI76_RS21805 +0.2
Sulfate permease, Trk-type No genes
Sulfate transport system permease protein CysT BWI76_RS20700 -1.5
Sulfate transport system permease protein CysW BWI76_RS20695 -2.2
Sulfate transporter, CysZ-type BWI76_RS20635 +0.2
Sulfite reductase [NADPH] flavoprotein alpha-component (EC 1.8.1.2) BWI76_RS22765 -4.3
Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) BWI76_RS22760 -4.5

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