| Role | Gene | Name | outer cut, LB soft agar motility assay | |
| | | ⨯ | |
| 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17) | AO353_13035 | | N.D. | |
| ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) | AO353_20175 | | -1.0 | |
| Adenine phosphoribosyltransferase (EC 2.4.2.7) | AO353_00665 | | +1.2 | |
| Adenylate cyclase (EC 4.6.1.1) | AO353_08695 | | +1.2 | |
| | AO353_09020 | | +1.2 | |
| | AO353_28480 | | -0.3 | |
| Adenylate/guanylate cyclase (EC 4.6.1.2) | No genes | | | |
| CAMP phosphodiesterases class-II:Metallo-beta-lactamase superfamily | No genes | | | |
| Cyclic AMP receptor protein | AO353_07200 | | +1.5 | |
| ElaA protein | AO353_07870 | | +0.4 | |
| Heme-regulated cyclic AMP phosphodiesterase (EC 3.1.4.-) | No genes | | | |
| Hydrolase, alpha/beta fold family functionally coupled to Phosphoribulokinase | AO353_02255 | | -0.0 | |
| | AO353_08270 | | +0.1 | |
| Predicted signal-transduction protein containing cAMP-binding and CBS domains | AO353_07570 | | -0.2 | |
| Prophage Clp protease-like protein | No genes | | | |
| Purine cyclase-related protein | No genes | | | |
| Putative Heme-regulated two-component response regulator | No genes | | | |
| Putative hemin-binding lipoprotein | No genes | | | |
| Putative insecticidal toxin complex | AO353_04740 | | +0.1 | |
| | AO353_04750 | | -0.0 | |
| | AO353_05870 | | -0.0 | |
| adenylate cyclase ExoY | No genes | | | |
| anthrax toxin moiety, protective antigen, pagA formerly pag, plasmid pXO1, B. anthracis (M22589, P13423) | No genes | | | |
| bifunctional hemolysin-adenylate cyclase precursor | No genes | | | |
| cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases | AO353_22285 | | -0.3 | |
| | AO353_24880 | | -0.3 | |
| | AO353_24885 | | -0.3 | |
| cAMP-dependent Kef-type K+ transport system | No genes | | | |
| calmodulin sensitive adenylate cyclase, edema factor, cya, plasmid pXO1, B. anthracis (M23179, M24074) | No genes | | | |
| cyclolysin secretion ATP-binding protein | No genes | | | |
| cyclolysin secretion protein | No genes | | | |
| cyclolysin-activating lysine-acyltransferase | No genes | | | |
| trans-acting positive regulator (Atx A) | No genes | | | |
| transcriptional activator AtxA, (pXO1-119) | No genes | | | |