SEED Subsystem: DNA-replication in Cupriavidus basilensis FW507-4G11

Experiments:

Role Gene Name R2A with Lomefloxacin 0.001 mM  
⨯
ATP-dependent DNA helicase RecG (EC 3.6.1.-) RR42_RS17390 -1.2
ATP-dependent DNA helicase RecQ RR42_RS19310 +2.4
Arrested fork binding No genes
Chromosomal replication initiator protein DnaA RR42_RS00005 N.D.
  RR42_RS17225 N.D.
Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) RR42_RS02715 N.D.
DNA polymerase I (EC 2.7.7.7) RR42_RS15050 -1.6
  RR42_RS26565 +0.2
DNA polymerase II (EC 2.7.7.7) RR42_RS09335 +0.2
DNA polymerase III alpha subunit (EC 2.7.7.7) RR42_RS04650 N.D.
  RR42_RS25820 -0.4
  RR42_RS32795 +0.3
DNA polymerase III beta subunit (EC 2.7.7.7) RR42_RS00010 N.D.
DNA polymerase III chi subunit (EC 2.7.7.7) RR42_RS16220 -0.2
DNA polymerase III delta prime subunit (EC 2.7.7.7) RR42_RS10900 N.D.
DNA polymerase III delta subunit (EC 2.7.7.7) RR42_RS17535 N.D.
DNA polymerase III epsilon subunit (EC 2.7.7.7) RR42_RS13585 N.D.
  RR42_RS36200 +0.0
DNA polymerase III psi subunit (EC 2.7.7.7) No genes
DNA polymerase III subunits gamma and tau (EC 2.7.7.7) RR42_RS13285 N.D.
DNA polymerase III theta subunit (EC 2.7.7.7) No genes
DNA primase (EC 2.7.7.-) RR42_RS14975 N.D.
DNA primase (EC 2.7.7.-), phage-associated No genes
DNA primase TraC (EC 2.7.7.-) No genes
DNA repair protein RecN RR42_RS05910 -1.7
DNA replication protein DnaC No genes
DNA replication terminus site-binding protein No genes
Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) No genes
Exodeoxyribonuclease V beta chain (EC 3.1.11.5) No genes
Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) No genes
Helicase PriA essential for oriC/DnaA-independent DNA replication RR42_RS20130 N.D.
Helicase loader DnaI No genes
Holliday junction DNA helicase RuvA RR42_RS02705 -0.4
Holliday junction DNA helicase RuvB RR42_RS02700 N.D.
Primosomal protein I No genes
Primosomal replication protein N RR42_RS12600 N.D.
Primosomal replication protein N prime prime No genes
RecA protein RR42_RS03080 -4.4
Recombination protein RecR RR42_RS13270 -0.3
Replicative DNA helicase (EC 3.6.1.-) RR42_RS12585 N.D.
Replicative DNA helicase (EC 3.6.1.-) [SA14-24] No genes
Single-stranded-DNA-specific exonuclease RecJ (EC 3.1.-.-) RR42_RS06090 +0.6
Transcription-repair coupling factor RR42_RS07845 +0.2

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