SEED Subsystem: Sialic Acid Metabolism in Bifidobacterium breve UCC2003

Experiments:

Role Gene Name Recovery broth with Bicyclomycin 0.07 mM  
ABC transporter, predicted N-acetylneuraminate transport system permease protein 1 No genes
ABC transporter, predicted N-acetylneuraminate transport system permease protein 2 No genes
ABC transporter, predicted N-acetylneuraminate-binding protein No genes
Beta-1,4-N-acetylgalactosaminyltransferase (EC 2.4.1.-) No genes
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase (EC 2.4.99.-) No genes
Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) BBR_RS13070 -2.5
Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157) BBR_RS14415 N.D.
Glucosamine-6-phosphate deaminase (EC 3.5.99.6) BBR_RS11140 +0.1
  BBR_RS14800 -0.0
  BBR_RS16865 +0.3
N-Acetylneuraminate cytidylyltransferase (EC 2.7.7.43) No genes
N-acetylglucosamine-1-phosphate uridyltransferase (EC 2.7.7.23) BBR_RS14415 N.D.
N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25) BBR_RS11145 -1.5
  BBR_RS14795 -0.1
  BBR_RS16860 +0.0
N-acetylmannosamine kinase (EC 2.7.1.60) BBR_RS11100 +0.1
  BBR_RS16870 -0.4
  BBR_RS18130 +8.0
N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9) BBR_RS11105 -0.2
N-acetylneuraminate lyase (EC 4.1.3.3) No genes
N-acetylneuraminate mutarotase No genes
N-acetylneuraminate synthase (EC 2.5.1.56) No genes
N-acetylneuraminic acid outer membrane channel protein NanC No genes
N-acylglucosamine 2-epimerase (EC 5.1.3.8) BBR_RS16325 +0.1
PTS system, N-acetylglucosamine-specific IIA component (EC 2.7.1.69) No genes
PTS system, N-acetylglucosamine-specific IIB component (EC 2.7.1.69) No genes
PTS system, N-acetylglucosamine-specific IIC component (EC 2.7.1.69) No genes
PTS system, N-acetylmuramic acid-specific IIB component (EC 2.7.1.69) No genes
PTS system, N-acetylmuramic acid-specific IIC component (EC 2.7.1.69) No genes
PTS system, mannose-specific IIA component (EC 2.7.1.69) No genes
PTS system, mannose-specific IIB component (EC 2.7.1.69) No genes
PTS system, mannose-specific IIC component (EC 2.7.1.69) No genes
PTS system, mannose-specific IID component (EC 2.7.1.69) No genes
Phosphoglucosamine mutase (EC 5.4.2.10) BBR_RS13010 N.D.
Predicted sialic acid transporter No genes
Putative sugar isomerase involved in processing of exogenous sialic acid No genes
Sialic acid biosynthesis protein NeuD, O-acetyltransferase No genes
Sialic acid transporter (permease) NanT No genes
Sialic acid utilization regulator, RpiR family BBR_RS13225 -0.1
Sialic acid-induced transmembrane protein YjhT(NanM), possible mutarotase No genes
Sialidase (EC 3.2.1.18) BBR_RS11150 +0.0
TRAP-type transport system, large permease component, predicted N-acetylneuraminate transporter No genes
TRAP-type transport system, periplasmic component, predicted N-acetylneuraminate-binding protein No genes
TRAP-type transport system, small permease component, predicted N-acetylneuraminate transporter No genes
Transcriptional regulator NanR No genes
UDP-N-acetylglucosamine 2-epimerase (EC 5.1.3.14) BBR_RS16870 -0.4

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