SEED Subsystem: Isoleucine degradation in Burkholderia phytofirmans PsJN

Experiments:

Role Gene Name L-Isoleucine (N)  
⨯
3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) BPHYT_RS03225 +0.3
  BPHYT_RS06760 +0.1
  BPHYT_RS09560 +0.2
  BPHYT_RS13545 +0.1
  BPHYT_RS34155 -0.2
3-ketoacyl-CoA thiolase (EC 2.3.1.16) BPHYT_RS02230 +0.2
  BPHYT_RS09565 -0.5
3-ketoacyl-CoA thiolase [isoleucine degradation] (EC 2.3.1.16) No genes
Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2) BPHYT_RS03000 +0.1
  BPHYT_RS08510 +0.2
  BPHYT_RS20780 +0.2
Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12) No genes
Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4) No genes
Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4) No genes
Branched-chain amino acid aminotransferase (EC 2.6.1.42) BPHYT_RS16285 -2.4
Butyrate kinase (EC 2.7.2.7) No genes
Butyryl-CoA dehydrogenase (EC 1.3.99.2) BPHYT_RS00670 +0.0
  BPHYT_RS02220 -1.0
  BPHYT_RS08290 -0.2
  BPHYT_RS20325 +0.3
  BPHYT_RS25370 +0.5
  BPHYT_RS25400 -0.2
  BPHYT_RS28040 +0.5
Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168) No genes
Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase (EC 1.8.1.4) No genes
Enoyl-CoA hydratase (EC 4.2.1.17) BPHYT_RS02345 -0.1
  BPHYT_RS03225 +0.3
  BPHYT_RS03235 +0.4
  BPHYT_RS03825 N.D.
  BPHYT_RS08375 N.D.
  BPHYT_RS08630 -0.2
  BPHYT_RS09560 +0.2
  BPHYT_RS10815 N.D.
  BPHYT_RS11780 N.D.
  BPHYT_RS13545 +0.1
  BPHYT_RS14830 -0.2
  BPHYT_RS25360 N.D.
  BPHYT_RS25695 N.D.
  BPHYT_RS27105 -0.0
  BPHYT_RS27895 -0.1
  BPHYT_RS28620 -0.4
  BPHYT_RS35465 -0.1
Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17) BPHYT_RS28020 N.D.
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.-) No genes
Predicted transcriptional regulator of leucine degradation pathway, MerR family No genes
Probable acyl-CoA dehydrogenase (EC 1.3.99.3) BPHYT_RS32685 -0.2
Transcriptional regulator BkdR of isoleucine and valine catabolism operon BPHYT_RS19770 -2.6
phosphotransbutyrylase (EC 2.3.1.19) No genes

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