SEED Subsystem: Methionine Biosynthesis in Burkholderia phytofirmans PsJN

Experiments:

Role Gene Name L-Glutamic (N)  
⨯
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) BPHYT_RS18705 -2.4
5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) BPHYT_RS02305 -1.8
  BPHYT_RS02310 -1.6
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) BPHYT_RS26655 -0.7
Adenosylhomocysteinase (EC 3.3.1.1) BPHYT_RS17740 N.D.
  BPHYT_RS18715 N.D.
  BPHYT_RS19095 N.D.
Archaeal S-adenosylmethionine synthetase (EC 2.5.1.6) No genes
Betaine--homocysteine S-methyltransferase (EC 2.1.1.5) No genes
Cystathionine beta-lyase (EC 4.4.1.8) BPHYT_RS09190 +0.2
Cystathionine beta-lyase, type II (EC 4.4.1.8) No genes
Cystathionine beta-synthase (EC 4.2.1.22) No genes
Cystathionine gamma-lyase (EC 4.4.1.1) No genes
Cystathionine gamma-synthase (EC 2.5.1.48) No genes
Cysteine synthase (EC 2.5.1.47) No genes
Duplicated ATPase component MtsB of energizing module of methionine-regulated ECF transporter No genes
Homocysteine S-methyltransferase (EC 2.1.1.10) No genes
Homoserine O-acetyltransferase (EC 2.3.1.31) BPHYT_RS01595 -4.0
Homoserine O-succinyltransferase (EC 2.3.1.46) No genes
Homoserine dehydrogenase (EC 1.1.1.3) BPHYT_RS08955 -5.0
Homoserine kinase (EC 2.7.1.39) BPHYT_RS33645 -5.0
Methionine ABC transporter ATP-binding protein BPHYT_RS02385 N.D.
  BPHYT_RS14820 -0.0
  BPHYT_RS17765 -0.4
  BPHYT_RS22535 N.D.
  BPHYT_RS27760 +0.3
Methionine ABC transporter permease protein BPHYT_RS14815 +0.3
  BPHYT_RS22540 +0.5
Methionine ABC transporter substrate-binding protein BPHYT_RS02715 +0.4
  BPHYT_RS14810 -0.2
  BPHYT_RS22210 N.D.
  BPHYT_RS22525 +0.1
Methionine repressor MetJ No genes
Methionine synthase activation domain (EC 2.1.1.13) No genes
Methionine transporter MetT No genes
O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) BPHYT_RS07480 +0.4
  BPHYT_RS13720 +0.0
  BPHYT_RS33835 -4.8
O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) BPHYT_RS13720 +0.0
  BPHYT_RS33835 -4.8
Predicted regulator of methionine metabolism, ArsR family No genes
S-adenosylhomocysteine nucleosidase (EC 3.2.2.9) No genes
S-adenosylmethionine synthetase (EC 2.5.1.6) BPHYT_RS01675 N.D.
S-ribosylhomocysteine lyase (EC 4.4.1.21) No genes
SAM-dependent methlytransferase UbiG No genes
SAM-dependent methlytransferase YrrT No genes
Serine acetyltransferase (EC 2.3.1.30) BPHYT_RS12455 +0.2
  BPHYT_RS21290 +0.1
  BPHYT_RS29810 +0.2
Substrate-specific component MtsA of methionine-regulated ECF transporter No genes
Transcriptional activator MetR BPHYT_RS26650 N.D.
Transmembrane component MtsC of energizing module of methionine-regulated ECF transporter No genes

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