SEED Subsystem: Aromatic amino acid degradation in Cupriavidus basilensis FW507-4G11

Experiments:

Role Gene Name L-Tryptophan (N)  
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase (EC 4.1.2.-) No genes
2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) RR42_RS27825 -0.1
  RR42_RS27830 +0.1
2-oxo-hepta-3-ene-1,7-dioic acid hydratase (EC 4.2.-.-) RR42_RS27850 -0.0
3,4-dihydroxyphenylacetate 2,3-dioxygenase (EC 1.13.11.15) RR42_RS27840 +0.0
4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) RR42_RS32440 -0.1
  RR42_RS32485 -0.0
  RR42_RS33500 +0.7
5-carboxymethyl-2-hydroxymuconate delta-isomerase (EC 5.3.3.10) RR42_RS27845 -0.2
  RR42_RS29125 N.D.
5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase (EC 1.2.1.60) RR42_RS27835 -0.0
5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) RR42_RS27825 -0.1
  RR42_RS27830 +0.1
5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase. RR42_RS00385 -0.2
Anthranilate dioxygenase large subunit No genes
Anthranilate dioxygenase reductase No genes
Anthranilate dioxygenase small subunit No genes
Aromatic amino acid transport protein AroP RR42_RS33495 +0.6
  RR42_RS33780 -0.1
Aromatic ring-opening dioxygenase No genes
Aromatic-L-amino-acid decarboxylase (EC 4.1.1.28) RR42_RS26695 -0.0
Homoprotocatechuate degradative operon repressor RR42_RS07320 N.D.
Indoleacetamide hydrolase (EC 3.5.1.-) No genes
Kynurenine formamidase, bacterial (EC 3.5.1.9) RR42_RS15380 -2.8
  RR42_RS33590 +0.1
Phenylalanine hydroxylase transcriptional activator PhhR No genes
Phenylalanine-4-hydroxylase (EC 1.14.16.1) RR42_RS20365 +0.2
Phenylalanine-specific permease RR42_RS05070 -0.0
Predicted 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase No genes
Probable 5-carboxymethyl-2-hydroxymuconate delta isomerase No genes
Putative 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase No genes
Putative 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase oxidoreductase protein (EC 1.2.1.60) RR42_RS32650 +0.1
Putative fumarylacetoacetate (FAA) hydrolase No genes
Tryptophan 2,3-dioxygenase (EC 1.13.11.11) RR42_RS15390 -3.4
Tryptophan 2-monooxygenase (EC 1.13.12.3) No genes
Tryptophanase (EC 4.1.99.1) No genes

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