SEED Subsystem: One-carbon metabolism by tetrahydropterines in Sinorhizobium meliloti 1021

Experiments:

Role Gene Name LB, pH8  
⨯
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) SMa2143 +0.3
  SMc01843 +1.0
  SMc04340 -1.5
5-FCL-like protein, but predicted not to be 5-formyltetrahydrofolate cyclo-ligase (5-FCL) No genes
5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) SMc02594 +0.2
  SMc03974 +1.0
F420-dependent methylenetetrahydromethanopterin dehydrogenase (EC 1.5.99.9) No genes
Formate--tetrahydrofolate ligase (EC 6.3.4.3) SMc02728 -0.1
Formiminotetrahydrofolate cyclodeaminase (EC 4.3.1.4) No genes
Formyltetrahydrofolate deformylase (EC 3.5.1.10) SMa2141 +0.2
  SMc03205 N.D.
  SMc04154 N.D.
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) SMc02604 -0.1
  SMc03059 N.D.
Methylene tetrahydromethanopterin dehydrogenase (EC 1.5.99.9) No genes
Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) SMc02604 -0.1
  SMc03059 N.D.
N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase (EC 3.5.4.27) No genes

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