SEED Subsystem: Valine degradation in Ralstonia sp. UNC404CL21Col

Experiments:

Role Gene Name Beta-alanine (C)  
⨯
3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) ABZR87_RS07480 -0.1
  ABZR87_RS12585 -0.1
  ABZR87_RS14655 -0.0
  ABZR87_RS23345 -0.1
3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) ABZR87_RS17475 +0.1
3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) ABZR87_RS17485 -0.1
Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12) No genes
Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4) No genes
Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4) No genes
Branched-chain amino acid aminotransferase (EC 2.6.1.42) ABZR87_RS18540 -0.1
Butyrate kinase (EC 2.7.2.7) No genes
Butyryl-CoA dehydrogenase (EC 1.3.99.2) ABZR87_RS06200 -0.4
  ABZR87_RS07825 -0.0
  ABZR87_RS16550 +0.1
  ABZR87_RS17460 -0.2
  ABZR87_RS20395 +0.2
  ABZR87_RS20865 -0.3
Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168) No genes
Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase (EC 1.8.1.4) No genes
Enoyl-CoA hydratase (EC 4.2.1.17) ABZR87_RS06190 -0.3
  ABZR87_RS06470 -0.0
  ABZR87_RS07480 -0.1
  ABZR87_RS07495 +0.2
  ABZR87_RS11295 -0.1
  ABZR87_RS12585 -0.1
  ABZR87_RS14660 +0.0
  ABZR87_RS16545 -0.2
  ABZR87_RS16935 -0.0
  ABZR87_RS20900 +0.0
  ABZR87_RS21810 -0.1
Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) ABZR87_RS17480 N.D.
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.-) No genes
Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) ABZR87_RS17470 +0.3
  ABZR87_RS19665 -4.9
Predicted transcriptional regulator of leucine degradation pathway, MerR family No genes
Probable acyl-CoA dehydrogenase (EC 1.3.99.3) No genes
Transcriptional regulator BkdR of isoleucine and valine catabolism operon No genes
phosphotransbutyrylase (EC 2.3.1.19) No genes

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