SEED Subsystem: Peptidoglycan Biosynthesis in Pseudomonas fluorescens FW300-N1B4

Experiments:

Role Gene Name Cisplatin 0.006 mg/ml  
Cell division protein FtsI [Peptidoglycan synthetase] (EC 2.4.1.129) Pf1N1B4_185 -0.1
  Pf1N1B4_949 N.D.
D-alanine--D-alanine ligase (EC 6.3.2.4) Pf1N1B4_941 N.D.
D-alanine--D-alanine ligase A (EC 6.3.2.4) No genes
D-alanine--D-alanine ligase B (EC 6.3.2.4) No genes
D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) Pf1N1B4_2696 N.D.
  Pf1N1B4_3846 +0.3
Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157) Pf1N1B4_1945 N.D.
Glutamate racemase (EC 5.1.1.3) Pf1N1B4_2922 N.D.
Glutamine synthetase type I (EC 6.3.1.2) Pf1N1B4_1606 N.D.
Glutamine synthetase type II, eukaryotic (EC 6.3.1.2) No genes
Glutamine synthetase type III, GlnN (EC 6.3.1.2) No genes
Glutamine synthetase, clostridia type (EC 6.3.1.2) No genes
Membrane-bound lytic murein transglycosylase B (EC 3.2.1.-) No genes
Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-) Pf1N1B4_2694 +1.5
  Pf1N1B4_2701 +1.4
Monofunctional biosynthetic peptidoglycan transglycosylase (EC 2.4.2.-) Pf1N1B4_2328 -0.1
Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) Pf1N1B4_1544 -0.8
  Pf1N1B4_2874 -2.7
Murein-DD-endopeptidase (EC 3.4.99.-) Pf1N1B4_3942 -0.5
N-acetylglucosamine-1-phosphate uridyltransferase (EC 2.7.7.23) Pf1N1B4_1945 N.D.
N-acetylglucosamine-1-phosphate uridyltransferase eukaryotic (EC 2.7.7.23) No genes
Penicillin-binding protein 2 (PBP-2) Pf1N1B4_2692 N.D.
Penicillin-binding protein 4 precursor No genes
Penicillin-binding protein PBP2a, methicillin resistance determinant MecA, transpeptidase No genes
Penicillin-insensitive transglycosylase (EC 2.4.2.-) & transpeptidase PBP-1C No genes
Phospho-N-acetylmuramoyl-pentapeptide-transferase (EC 2.7.8.13) Pf1N1B4_946 N.D.
Putative glutamine synthetase, Rickettsiales type (EC 6.3.1.2) No genes
Rare lipoprotein A precursor Pf1N1B4_2695 +1.1
Rod shape-determining protein RodA Pf1N1B4_2693 N.D.
UDP-N-acetylenolpyruvoylglucosamine reductase (EC 1.1.1.158) Pf1N1B4_466 N.D.
UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) Pf1N1B4_1068 N.D.
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (EC 2.4.1.227) Pf1N1B4_943 N.D.
UDP-N-acetylmuramate--alanine ligase (EC 6.3.2.8) Pf1N1B4_942 N.D.
UDP-N-acetylmuramoylalanine--D-glutamate ligase (EC 6.3.2.9) Pf1N1B4_945 N.D.
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase (EC 6.3.2.13) Pf1N1B4_948 N.D.
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase (EC 6.3.2.10) Pf1N1B4_947 N.D.

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