SEED Subsystem: Methionine Biosynthesis in Klebsiella michiganensis M5al

Experiments:

Role Gene Name Supernatant; Trichoderma atroviride IMI grown in Vogels_fungal_media, non-filtered; 1X  
⨯
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) BWI76_RS00805 -6.5
5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) BWI76_RS01685 -0.2
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) BWI76_RS01280 -2.7
  BWI76_RS15390 +0.1
Adenosylhomocysteinase (EC 3.3.1.1) BWI76_RS18745 -0.2
Archaeal S-adenosylmethionine synthetase (EC 2.5.1.6) No genes
Betaine--homocysteine S-methyltransferase (EC 2.1.1.5) No genes
Cystathionine beta-lyase (EC 4.4.1.8) BWI76_RS24285 -5.7
Cystathionine beta-lyase, type II (EC 4.4.1.8) No genes
Cystathionine beta-synthase (EC 4.2.1.22) BWI76_RS24205 +0.3
Cystathionine gamma-lyase (EC 4.4.1.1) BWI76_RS24210 -0.1
Cystathionine gamma-synthase (EC 2.5.1.48) BWI76_RS00785 -3.9
  BWI76_RS16730 -0.1
Cysteine synthase (EC 2.5.1.47) BWI76_RS20640 -1.6
Duplicated ATPase component MtsB of energizing module of methionine-regulated ECF transporter No genes
Homocysteine S-methyltransferase (EC 2.1.1.10) BWI76_RS06030 -0.0
Homoserine O-acetyltransferase (EC 2.3.1.31) No genes
Homoserine O-succinyltransferase (EC 2.3.1.46) BWI76_RS01655 -4.6
Homoserine dehydrogenase (EC 1.1.1.3) BWI76_RS00790 -0.2
  BWI76_RS04245 -4.2
Homoserine kinase (EC 2.7.1.39) BWI76_RS04250 -5.7
Methionine ABC transporter ATP-binding protein BWI76_RS05365 -0.1
  BWI76_RS15030 -0.1
  BWI76_RS16675 +0.2
Methionine ABC transporter permease protein BWI76_RS05360 +0.1
  BWI76_RS15035 -0.5
  BWI76_RS16665 -0.1
Methionine ABC transporter substrate-binding protein BWI76_RS05355 +0.4
  BWI76_RS15025 N.D.
  BWI76_RS16320 +0.4
  BWI76_RS16670 -0.0
  BWI76_RS17105 +0.3
  BWI76_RS27655 +0.0
Methionine repressor MetJ BWI76_RS00780 N.D.
Methionine synthase activation domain (EC 2.1.1.13) No genes
Methionine transporter MetT No genes
O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) No genes
O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) No genes
Predicted regulator of methionine metabolism, ArsR family No genes
S-adenosylhomocysteine nucleosidase (EC 3.2.2.9) BWI76_RS05170 N.D.
S-adenosylmethionine synthetase (EC 2.5.1.6) BWI76_RS24050 N.D.
S-ribosylhomocysteine lyase (EC 4.4.1.21) BWI76_RS22115 -0.2
SAM-dependent methlytransferase UbiG No genes
SAM-dependent methlytransferase YrrT No genes
Serine acetyltransferase (EC 2.3.1.30) BWI76_RS05560 N.D.
  BWI76_RS27205 N.D.
Substrate-specific component MtsA of methionine-regulated ECF transporter No genes
Transcriptional activator MetR BWI76_RS01275 -4.5
Transmembrane component MtsC of energizing module of methionine-regulated ECF transporter No genes

Or select organism:

Or view this subsystem at the SEED (slow)