SEED Subsystem: Methionine Biosynthesis in Synechocystis sp000284455 PCC 6803

Experiments:

Role Gene Name growth in media lacking HCO3 but diluted to prevent light attenuation  
⨯
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) SGL_RS07805 N.D.
5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) SGL_RS14710 N.D.
  SGL_RS14745 -0.1
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) No genes
Adenosylhomocysteinase (EC 3.3.1.1) SGL_RS09665 N.D.
Archaeal S-adenosylmethionine synthetase (EC 2.5.1.6) No genes
Betaine--homocysteine S-methyltransferase (EC 2.1.1.5) No genes
Cystathionine beta-lyase (EC 4.4.1.8) No genes
Cystathionine beta-lyase, type II (EC 4.4.1.8) No genes
Cystathionine beta-synthase (EC 4.2.1.22) No genes
Cystathionine gamma-lyase (EC 4.4.1.1) No genes
Cystathionine gamma-synthase (EC 2.5.1.48) No genes
Cysteine synthase (EC 2.5.1.47) SGL_RS02310 -0.1
  SGL_RS06370 -0.5
Duplicated ATPase component MtsB of energizing module of methionine-regulated ECF transporter No genes
Homocysteine S-methyltransferase (EC 2.1.1.10) SGL_RS18175 +0.4
Homoserine O-acetyltransferase (EC 2.3.1.31) No genes
Homoserine O-succinyltransferase (EC 2.3.1.46) No genes
Homoserine dehydrogenase (EC 1.1.1.3) SGL_RS08310 N.D.
  SGL_RS14120 N.D.
Homoserine kinase (EC 2.7.1.39) SGL_RS05965 +0.2
  SGL_RS07645 N.D.
Methionine ABC transporter ATP-binding protein SGL_RS05900 -3.4
  SGL_RS07030 N.D.
  SGL_RS11145 N.D.
  SGL_RS15420 +0.4
Methionine ABC transporter permease protein No genes
Methionine ABC transporter substrate-binding protein No genes
Methionine repressor MetJ No genes
Methionine synthase activation domain (EC 2.1.1.13) No genes
Methionine transporter MetT No genes
O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) No genes
O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) No genes
Predicted regulator of methionine metabolism, ArsR family No genes
S-adenosylhomocysteine nucleosidase (EC 3.2.2.9) No genes
S-adenosylmethionine synthetase (EC 2.5.1.6) SGL_RS03470 N.D.
S-ribosylhomocysteine lyase (EC 4.4.1.21) No genes
SAM-dependent methlytransferase UbiG No genes
SAM-dependent methlytransferase YrrT No genes
Serine acetyltransferase (EC 2.3.1.30) SGL_RS10115 N.D.
Substrate-specific component MtsA of methionine-regulated ECF transporter No genes
Transcriptional activator MetR No genes
Transmembrane component MtsC of energizing module of methionine-regulated ECF transporter No genes

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