SEED Subsystem: Methionine Biosynthesis in Pantoea sp. MT58

Experiments:

Role Gene Name copper (II) chloride 2 uM, anaerobic  
⨯
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) IAI47_00890 -1.1
5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) IAI47_17990 -0.2
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) IAI47_18310 -0.4
  IAI47_20755 +0.1
Adenosylhomocysteinase (EC 3.3.1.1) No genes
Archaeal S-adenosylmethionine synthetase (EC 2.5.1.6) No genes
Betaine--homocysteine S-methyltransferase (EC 2.1.1.5) No genes
Cystathionine beta-lyase (EC 4.4.1.8) IAI47_03215 -0.2
Cystathionine beta-lyase, type II (EC 4.4.1.8) IAI47_08380 -0.3
Cystathionine beta-synthase (EC 4.2.1.22) No genes
Cystathionine gamma-lyase (EC 4.4.1.1) No genes
Cystathionine gamma-synthase (EC 2.5.1.48) IAI47_00880 -1.3
  IAI47_15695 +0.8
Cysteine synthase (EC 2.5.1.47) IAI47_05405 +2.9
  IAI47_05440 -0.4
  IAI47_14605 -0.0
Duplicated ATPase component MtsB of energizing module of methionine-regulated ECF transporter No genes
Homocysteine S-methyltransferase (EC 2.1.1.10) IAI47_04565 -0.3
Homoserine O-acetyltransferase (EC 2.3.1.31) No genes
Homoserine O-succinyltransferase (EC 2.3.1.46) IAI47_18015 -1.1
Homoserine dehydrogenase (EC 1.1.1.3) IAI47_00885 -0.0
  IAI47_16215 -0.9
Homoserine kinase (EC 2.7.1.39) IAI47_16210 -1.2
Methionine ABC transporter ATP-binding protein IAI47_15385 -0.5
  IAI47_20045 +0.0
  IAI47_20555 +0.2
Methionine ABC transporter permease protein IAI47_15390 -0.4
  IAI47_20550 -0.2
Methionine ABC transporter substrate-binding protein IAI47_15395 +0.2
  IAI47_20145 -0.4
  IAI47_20560 -0.3
Methionine repressor MetJ IAI47_00875 -0.7
Methionine synthase activation domain (EC 2.1.1.13) No genes
Methionine transporter MetT No genes
O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) No genes
O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) No genes
Predicted regulator of methionine metabolism, ArsR family No genes
S-adenosylhomocysteine nucleosidase (EC 3.2.2.9) No genes
S-adenosylmethionine synthetase (EC 2.5.1.6) IAI47_03655 N.D.
S-ribosylhomocysteine lyase (EC 4.4.1.21) IAI47_04355 +0.6
SAM-dependent methlytransferase UbiG No genes
SAM-dependent methlytransferase YrrT No genes
Serine acetyltransferase (EC 2.3.1.30) IAI47_00745 N.D.
Substrate-specific component MtsA of methionine-regulated ECF transporter No genes
Transcriptional activator MetR IAI47_18315 -0.3
Transmembrane component MtsC of energizing module of methionine-regulated ECF transporter No genes

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