SEED Subsystem: Valine degradation in Sinorhizobium meliloti 1021

Experiments:

Role Gene Name Uridine (C)  
⨯
3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) SM_b21632 +0.2
  SMc02227 -1.2
3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) SM_b20710 -0.2
  SM_b20751 -0.4
  SMa0516 +0.0
3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) SM_b20752 +0.2
Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12) No genes
Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4) SM_b20020 -0.2
  SMc03201 +0.1
Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4) SM_b20020 -0.2
  SMc03202 +0.1
Branched-chain amino acid aminotransferase (EC 2.6.1.42) SMc00042 +0.2
  SMc02896 -0.0
Butyrate kinase (EC 2.7.2.7) No genes
Butyryl-CoA dehydrogenase (EC 1.3.99.2) SMa1400 -0.1
  SMa2089 +0.2
  SMa2091 +0.3
  SMc01639 +0.0
Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168) SM_b20019 -0.0
  SMc03203 +0.1
Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase (EC 1.8.1.4) SMc03204 +0.2
Enoyl-CoA hydratase (EC 4.2.1.17) SM_b21632 +0.2
  SM_b21633 +0.8
  SMc00976 +0.5
  SMc01638 +0.1
  SMc01669 +0.2
  SMc01806 -0.1
Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) No genes
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.-) No genes
Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) SMc00781 -2.4
Predicted transcriptional regulator of leucine degradation pathway, MerR family No genes
Probable acyl-CoA dehydrogenase (EC 1.3.99.3) No genes
Transcriptional regulator BkdR of isoleucine and valine catabolism operon No genes
phosphotransbutyrylase (EC 2.3.1.19) No genes

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