MetaCyc Pathway: L-tyrosine degradation I in Pseudomonas fluorescens FW300-N2E2

Add experiment(s):


Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
Pf6N2E2_1496
Pf6N2E2_2127
Pf6N2E2_2446
Pf6N2E2_2519
Pf6N2E2_2632
Pf6N2E2_3173
Pf6N2E2_3251
Pf6N2E2_4288
Pf6N2E2_4386
Pf6N2E2_462
Pf6N2E2_50
Pf6N2E2_5300
Pf6N2E2_5813
Pf6N2E2_5890
Pf6N2E2_5891
Pf6N2E2_5895
Pf6N2E2_5989
Pf6N2E2_637
Pf6N2E2_684
4-hydroxyphenylpyruvate dioxygenase:
3-(4-hydroxyphenyl)pyruvate + dioxygen→homogentisate + CO2 (EC 1.13.11.27)
Pf6N2E2_1001
Pf6N2E2_456
Pf6N2E2_5058
Pf6N2E2_988
Homogentisate 1,2-dioxygenase:
homogentisate + dioxygen→4-maleyl-acetoacetate + H+ (EC 1.13.11.5)
Pf6N2E2_5290
Maleylacetoacetate isomerase:
4-maleyl-acetoacetate→4-fumaryl-acetoacetate (EC 5.2.1.2)
Pf6N2E2_5292
Fumarylacetoacetase:
4-fumaryl-acetoacetate + H2O→acetoacetate + fumarate + H+ (EC 3.7.1.2)
Pf6N2E2_5291

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information