MetaCyc Pathway: ketogenesis in Pseudomonas fluorescens FW300-N2E2

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Acetyl-CoA C-acyltransferase:
2 acetyl-CoA→acetoacetyl-CoA + coenzyme A (EC 2.3.1.16; 2.3.1.9)
Pf6N2E2_1145
Pf6N2E2_1675
Pf6N2E2_1836
Pf6N2E2_1851
Pf6N2E2_1923
Pf6N2E2_2113
Pf6N2E2_2289
Pf6N2E2_2539
Pf6N2E2_2835
Pf6N2E2_3492
Pf6N2E2_5999
Hydroxymethylglutaryl-CoA synthase:
acetoacetyl-CoA + acetyl-CoA + H2O→(S)-3-hydroxy-3-methylglutaryl-CoA + coenzyme A + H+ (EC 2.3.3.10)
Pf6N2E2_1837
Hydroxymethylglutaryl-CoA lyase:
(S)-3-hydroxy-3-methylglutaryl-CoA→acetyl-CoA + acetoacetate (EC 4.1.3.4)
Pf6N2E2_1040
Pf6N2E2_1041
Pf6N2E2_2189
3-hydroxybutyrate dehydrogenase (in reverse):
acetoacetate + NADH + H+→(R)-3-hydroxybutanoate + NAD+ (EC 1.1.1.30)
Pf6N2E2_2041
Acetoacetate decarboxylase:
acetoacetate + H+→acetone + CO2 (EC 4.1.1.4)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information