MetaCyc Pathway: 2-allylmalonyl-CoA biosynthesis in Pseudomonas fluorescens FW300-N2E2

Add experiment(s):


propanoyl-CoA + TcsB polyketide synthase→propanoyl-[TcsB polyketide synthase] + coenzyme A
No genes
malonyl-CoA + TcsA polyketide synthase→malonyl-[TcsA polyketide synthase] + coenzyme A
No genes
malonyl-[TcsA polyketide synthase] + propanoyl-[TcsB polyketide synthase] + H+→3-oxopentanoyl-[TcsA polyketide synthase] + CO2 + TcsB polyketide synthase
No genes
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
3-oxopentanoyl-[TcsA polyketide synthase] + NADPH + H+→(3R)-3-hydroxypentanoyl-[TcsA polyketide synthase] + NADP+ (EC 1.1.1.100)
Pf6N2E2_1004
Pf6N2E2_1181
Pf6N2E2_1257
Pf6N2E2_1323
Pf6N2E2_1747
Pf6N2E2_1925
Pf6N2E2_1928
Pf6N2E2_3493
Pf6N2E2_3704
Pf6N2E2_3728
Pf6N2E2_383
Pf6N2E2_3916
Pf6N2E2_394
Pf6N2E2_4183
Pf6N2E2_5206
Pf6N2E2_5209
Pf6N2E2_5603
Pf6N2E2_5952
Pf6N2E2_5967
Pf6N2E2_6050
Pf6N2E2_686
Pf6N2E2_853
Pf6N2E2_990
Pf6N2E2_995
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
(3R)-3-hydroxypentanoyl-[TcsA polyketide synthase]→(2E)-pent-2-enoyl-[TcsA polyketide synthase] + H2O (EC 4.2.1.59)
Pf6N2E2_3058
Pf6N2E2_5871
(2E)-pent-2-enoyl-[TcsA polyketide synthase] + CO2 + NADPH→2-carboxypentanoyl-[TcsA polyketide synthase] + NADP+
No genes
2-carboxypentanoyl-[TcsA polyketide synthase] + FAD + H+→2-allylmalonyl-[TcsA polyketide synthase] + FADH2
No genes
2-allylmalonyl-[TcsA polyketide synthase] + coenzyme A→2-allylmalonyl-CoA + TcsA polyketide synthase
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information