MetaCyc Pathway: octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast) in Pseudomonas fluorescens FW300-N2E2

Add experiment(s):


Beta-ketoacyl-acyl-carrier-protein synthase II:
an acetyl-[acp] + a malonyl-[acp] + H+→an acetoacetyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
Pf6N2E2_1178
Pf6N2E2_3726
Pf6N2E2_3729
Pf6N2E2_5870
Pf6N2E2_5954
Pf6N2E2_835
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
an acetoacetyl-[acp] + NADPH + H+→a (3R)-3-hydroxybutanoyl-[acp] + NADP+ (EC 1.1.1.100)
Pf6N2E2_1004
Pf6N2E2_1181
Pf6N2E2_1257
Pf6N2E2_1323
Pf6N2E2_1747
Pf6N2E2_1925
Pf6N2E2_1928
Pf6N2E2_3493
Pf6N2E2_3704
Pf6N2E2_3728
Pf6N2E2_383
Pf6N2E2_3916
Pf6N2E2_394
Pf6N2E2_4183
Pf6N2E2_5206
Pf6N2E2_5209
Pf6N2E2_5603
Pf6N2E2_5952
Pf6N2E2_5967
Pf6N2E2_6050
Pf6N2E2_686
Pf6N2E2_853
Pf6N2E2_990
Pf6N2E2_995
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxybutanoyl-[acp]→a (2E)-but-2-enoyl-[acp] + H2O (EC 4.2.1.59)
Pf6N2E2_3058
Pf6N2E2_5871
Enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) (in reverse):
a (2E)-but-2-enoyl-[acp] + NADPH + H+→a butanoyl-[acp] + NADP+ (EC 1.3.1.10; 1.3.1.104; 1.3.1.39)
Pf6N2E2_1446
Beta-ketoacyl-acyl-carrier-protein synthase II:
a butanoyl-[acp] + a malonyl-[acp] + H+→a 3-oxohexanoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
Pf6N2E2_1178
Pf6N2E2_3726
Pf6N2E2_3729
Pf6N2E2_5870
Pf6N2E2_5954
Pf6N2E2_835
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxohexanoyl-[acp] + NADPH + H+→a (3R)-3-hydroxyhexanoyl-[acp] + NADP+ (EC 1.1.1.100)
Pf6N2E2_1004
Pf6N2E2_1181
Pf6N2E2_1257
Pf6N2E2_1323
Pf6N2E2_1747
Pf6N2E2_1925
Pf6N2E2_1928
Pf6N2E2_3493
Pf6N2E2_3704
Pf6N2E2_3728
Pf6N2E2_383
Pf6N2E2_3916
Pf6N2E2_394
Pf6N2E2_4183
Pf6N2E2_5206
Pf6N2E2_5209
Pf6N2E2_5603
Pf6N2E2_5952
Pf6N2E2_5967
Pf6N2E2_6050
Pf6N2E2_686
Pf6N2E2_853
Pf6N2E2_990
Pf6N2E2_995
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxyhexanoyl-[acp]→a (2E)-hex-2-enoyl-[acp] + H2O (EC 4.2.1.59)
Pf6N2E2_3058
Pf6N2E2_5871
Enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) (in reverse):
a (2E)-hex-2-enoyl-[acp] + NADPH + H+→a hexanoyl-[acp] + NADP+ (EC 1.3.1.10; 1.3.1.104; 1.3.1.39)
Pf6N2E2_1446
Beta-ketoacyl-acyl-carrier-protein synthase II:
a hexanoyl-[acp] + a malonyl-[acp] + H+→a 3-oxooctanoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
Pf6N2E2_1178
Pf6N2E2_3726
Pf6N2E2_3729
Pf6N2E2_5870
Pf6N2E2_5954
Pf6N2E2_835
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxooctanoyl-[acp] + NADPH + H+→a (3R)-3-hydroxyoctanoyl-[acp] + NADP+ (EC 1.1.1.100)
Pf6N2E2_1004
Pf6N2E2_1181
Pf6N2E2_1257
Pf6N2E2_1323
Pf6N2E2_1747
Pf6N2E2_1925
Pf6N2E2_1928
Pf6N2E2_3493
Pf6N2E2_3704
Pf6N2E2_3728
Pf6N2E2_383
Pf6N2E2_3916
Pf6N2E2_394
Pf6N2E2_4183
Pf6N2E2_5206
Pf6N2E2_5209
Pf6N2E2_5603
Pf6N2E2_5952
Pf6N2E2_5967
Pf6N2E2_6050
Pf6N2E2_686
Pf6N2E2_853
Pf6N2E2_990
Pf6N2E2_995
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxyoctanoyl-[acp]→a (2E)-oct-2-enoyl-[acp] + H2O (EC 4.2.1.59)
Pf6N2E2_3058
Pf6N2E2_5871
Enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) (in reverse):
a (2E)-oct-2-enoyl-[acp] + NADPH + H+→an octanoyl-[acp] + NADP+ (EC 1.3.1.10; 1.3.1.104; 1.3.1.39)
Pf6N2E2_1446

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information