MetaCyc Pathway: L-phenylalanine degradation IV (mammalian, via side chain) in Pseudomonas fluorescens FW300-N2E2

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Aromatic-L-amino-acid decarboxylase:
L-phenylalanine + H+→2-phenylethylamine + CO2 (EC 4.1.1.28; 4.1.1.53)
No genes
Aspartate transaminase:
L-phenylalanine + 2-oxoglutarate→3-phenyl-2-oxopropanoate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.57)
Pf6N2E2_1496
Pf6N2E2_2127
Pf6N2E2_2446
Pf6N2E2_2519
Pf6N2E2_2632
Pf6N2E2_3173
Pf6N2E2_3251
Pf6N2E2_4288
Pf6N2E2_4386
Pf6N2E2_462
Pf6N2E2_50
Pf6N2E2_5300
Pf6N2E2_5813
Pf6N2E2_5890
Pf6N2E2_5891
Pf6N2E2_5895
Pf6N2E2_5989
Pf6N2E2_637
Pf6N2E2_684
4-hydroxyphenylpyruvate dioxygenase:
3-phenyl-2-oxopropanoate + dioxygen→(2-hydroxyphenyl)acetate + CO2 (EC 1.13.11.27)
Pf6N2E2_1001
Pf6N2E2_456
Pf6N2E2_5058
Pf6N2E2_988
Indolelactate dehydrogenase (in reverse):
3-phenyl-2-oxopropanoate + NADH + H+→(R)-3-(phenyl)lactate + NAD+ (EC 1.1.1.110)
No genes
Primary-amine oxidase:
2-phenylethylamine + dioxygen + H2O→phenylacetaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.21; 1.4.3.4)
Pf6N2E2_4632
Phenylacetaldehyde dehydrogenase:
phenylacetaldehyde + NAD+ + H2O→phenylacetate + NADH + 2 H+ (EC 1.2.1.39)
Pf6N2E2_1329
Pf6N2E2_1381
Pf6N2E2_1764
Pf6N2E2_4979
Phenylacetate--CoA ligase:
phenylacetate + ATP + coenzyme A→phenylacetyl-CoA + AMP + diphosphate (EC 6.2.1.30)
Pf6N2E2_1716
Glutamine N-phenylacetyltransferase:
phenylacetyl-CoA + L-glutamine→α-N-phenylacetyl-L-glutamine + coenzyme A + H+ (EC 2.3.1.14)
No genes
phenylacetyl-CoA + glycine→phenylacetylglycine + coenzyme A + H+ (EC 2.3.1.192)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information