MetaCyc Pathway: glutathione-mediated detoxification I in Pseudomonas fluorescens FW300-N2E2

Add experiment(s):


Glutathione transferase:
RX + glutathione→a glutathione-S-conjugate + HX (EC 2.5.1.18)
Pf6N2E2_1445
Pf6N2E2_1553
Pf6N2E2_1561
Pf6N2E2_1619
Pf6N2E2_2148
Pf6N2E2_2168
Pf6N2E2_303
Pf6N2E2_395
Pf6N2E2_4178
Pf6N2E2_4235
Pf6N2E2_4428
Pf6N2E2_509
Pf6N2E2_5292
Pf6N2E2_5412
Pf6N2E2_5517
Pf6N2E2_5974
Pf6N2E2_6007
Pf6N2E2_933
a glutathione-S-conjugate[in] + ATP[in] + H2O[in]→a glutathione-S-conjugate[out] + ADP[in] + H+[in] + phosphate[in] (EC 7.6.2.3)
No genes
a glutathione-S-conjugate + H2O→an (L-cysteinylglycine)-S-conjugate + L-glutamate (EC 3.4.19.13)
No genes
an (L-cysteinylglycine)-S-conjugate + H2O→an L-cysteine-S-conjugate + glycine (EC 3.4.13.23)
No genes
Cysteine-S-conjugate N-acetyltransferase:
an L-cysteine-S-conjugate + acetyl-CoA→a mercapturate + coenzyme A + H+ (EC 2.3.1.80)
No genes
Cysteine-S-conjugate beta-lyase:
an L-cysteine-S-conjugate→2-aminoprop-2-enoate + a thiol (EC 4.4.1.13)
No genes
Tryptophanase:
2-aminoprop-2-enoate→2-iminopropanoate (spontaneous) (EC 4.1.99.1; 4.1.99.2; 4.3.1.13; 4.3.1.17; 4.3.1.18; 4.3.3.8; 4.4.1.1; 4.4.1.13; 4.4.1.15; 4.4.1.25; 4.4.1.28; 4.4.1.35; 4.5.1.2)
Pf6N2E2_2047
Pf6N2E2_3918
Pf6N2E2_4685
Pf6N2E2_5557
Pf6N2E2_5896
2-iminopropanoate + H2O→pyruvate + ammonium (spontaneous) (EC 3.5.99.10; 4.1.99.1; 4.1.99.2; 4.3.1.13; 4.3.1.17; 4.3.1.18; 4.3.3.8; 4.4.1.1; 4.4.1.13; 4.4.1.15; 4.4.1.25; 4.4.1.28; 4.4.1.35; 4.5.1.2)
Pf6N2E2_2047
Pf6N2E2_3918
Pf6N2E2_4360
Pf6N2E2_4685
Pf6N2E2_5557
Pf6N2E2_5896

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information