MetaCyc Pathway: 3-phenylpropanoate degradation in Pseudomonas fluorescens FW300-N2E2

Add experiment(s):


3-phenylpropanoate + ATP + coenzyme A→3-phenylpropanoyl-CoA + AMP + diphosphate
No genes
3-phenylpropanoyl-CoA + an oxidized electron carrier→(E)-cinnamoyl-CoA + a reduced two electron carrier
No genes
Enoyl-CoA hydratase (in reverse):
(E)-cinnamoyl-CoA + H2O→(S)-3-hydroxy-3-phenylpropanoyl-CoA (EC 4.2.1.17)
Pf6N2E2_1013
Pf6N2E2_1046
Pf6N2E2_1147
Pf6N2E2_1149
Pf6N2E2_1269
Pf6N2E2_1833
Pf6N2E2_1834
Pf6N2E2_1835
Pf6N2E2_1840
Pf6N2E2_1850
Pf6N2E2_1922
Pf6N2E2_1934
Pf6N2E2_1935
Pf6N2E2_2290
Pf6N2E2_2773
Pf6N2E2_3894
Pf6N2E2_5493
Pf6N2E2_6000
Pf6N2E2_6004
Pf6N2E2_742
3-hydroxyacyl-CoA dehydrogenase:
(S)-3-hydroxy-3-phenylpropanoyl-CoA + NAD+→3-oxo-3-phenylpropanoyl-CoA + NADH + H+ (EC 1.1.1.35)
Pf6N2E2_1833
Pf6N2E2_1850
Pf6N2E2_1922
Pf6N2E2_2290
Pf6N2E2_3894
Pf6N2E2_4690
Pf6N2E2_6000
Acetyl-CoA C-acyltransferase (in reverse):
3-oxo-3-phenylpropanoyl-CoA + coenzyme A→benzoyl-CoA + acetyl-CoA (EC 2.3.1.16)
Pf6N2E2_1145
Pf6N2E2_1675
Pf6N2E2_1836
Pf6N2E2_1851
Pf6N2E2_2113
Pf6N2E2_2289
Pf6N2E2_2539
Pf6N2E2_2835
Pf6N2E2_3492
Pf6N2E2_5999
Benzoyl-CoA 3-monooxygenase:
benzoyl-CoA + NADPH + dioxygen + H+→3-hydroxybenzoyl-CoA + NADP+ + H2O (EC 1.14.13.58)
No genes
3-hydroxybenzoyl-CoA + a reduced two electron carrier + dioxygen→gentisate + an oxidized electron carrier + coenzyme A + H+
No genes
Gentisate 1,2-dioxygenase:
gentisate + dioxygen→3-maleylpyruvate + H+ (EC 1.13.11.4)
No genes
Maleylpyruvate isomerase:
3-maleylpyruvate→3-fumarylpyruvate (EC 5.2.1.4)
Pf6N2E2_5292
3-fumarylpyruvate + H2O→fumarate + pyruvate + H+ (EC 3.7.1.20)
Pf6N2E2_6018

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information