MetaCyc Pathway: L-tyrosine degradation I in Pseudomonas fluorescens FW300-N2C3

Add experiment(s):


Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
AO356_01275
AO356_03090
AO356_03460
AO356_03985
AO356_06565
AO356_06960
AO356_12070
AO356_12595
AO356_16875
AO356_19495
AO356_19865
AO356_19905
AO356_20345
AO356_21330
AO356_22880
AO356_24005
AO356_24115
AO356_24720
AO356_24975
AO356_25355
4-hydroxyphenylpyruvate dioxygenase:
3-(4-hydroxyphenyl)pyruvate + dioxygen→homogentisate + CO2 (EC 1.13.11.27)
AO356_15580
AO356_22845
Homogentisate 1,2-dioxygenase:
homogentisate + dioxygen→4-maleyl-acetoacetate + H+ (EC 1.13.11.5)
AO356_16825
Maleylacetoacetate isomerase:
4-maleyl-acetoacetate→4-fumaryl-acetoacetate (EC 5.2.1.2)
AO356_16835
Fumarylacetoacetase:
4-fumaryl-acetoacetate + H2O→acetoacetate + fumarate + H+ (EC 3.7.1.2)
AO356_16830

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information