MetaCyc Pathway: superpathway of L-serine and glycine biosynthesis I in Pseudomonas fluorescens FW300-N2C3

Add experiment(s):


Phosphoglycerate dehydrogenase:
3-phospho-D-glycerate + NAD+→3-phosphooxypyruvate + NADH + H+ (EC 1.1.1.95)
AO356_04410
AO356_06935
AO356_10300
AO356_20675
AO356_24380
AO356_26030
AO356_26720
Phosphoserine transaminase (in reverse):
3-phosphooxypyruvate + L-glutamate→O-phospho-L-serine + 2-oxoglutarate (EC 2.6.1.52)
AO356_03470
Phosphoserine phosphatase:
O-phospho-L-serine + H2O→L-serine + phosphate (EC 3.1.3.3)
AO356_08735
AO356_10340
AO356_13245
AO356_19355
AO356_20835
AO356_23485
Glycine hydroxymethyltransferase:
L-serine + a tetrahydrofolate→glycine + a 5,10-methylenetetrahydrofolate + H2O (EC 2.1.2.1)
AO356_13970
AO356_15725
AO356_16850

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information