MetaCyc Pathway: benzoate biosynthesis I (CoA-dependent, β-oxidative) in Pseudomonas fluorescens FW300-N2C3

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Phenylalanine ammonia-lyase:
L-phenylalanine→trans-cinnamate + ammonium (EC 4.3.1.24; 4.3.1.25; 5.4.3.10)
No genes
trans-cinnamate + ATP + coenzyme A→(E)-cinnamoyl-CoA + AMP + diphosphate
AO356_29235
Enoyl-CoA hydratase (in reverse):
(E)-cinnamoyl-CoA + H2O→(S)-3-hydroxy-3-phenylpropanoyl-CoA (EC 4.2.1.17)
AO356_02330
AO356_04640
AO356_10120
AO356_12440
AO356_17825
AO356_20400
AO356_20420
AO356_25890
AO356_26360
AO356_26370
AO356_26645
AO356_27920
AO356_30295
AO356_30355
AO356_30360
3-hydroxyacyl-CoA dehydrogenase:
(S)-3-hydroxy-3-phenylpropanoyl-CoA + NAD+→3-oxo-3-phenylpropanoyl-CoA + NADH + H+ (EC 1.1.1.35)
AO356_02330
AO356_10120
AO356_13845
AO356_20400
AO356_30295
Acetyl-CoA C-acyltransferase (in reverse):
3-oxo-3-phenylpropanoyl-CoA + coenzyme A→benzoyl-CoA + acetyl-CoA (EC 2.3.1.16)
AO356_02325
AO356_03560
AO356_04930
AO356_08090
AO356_20395
AO356_21640
AO356_26350
benzoyl-CoA + H2O→benzoate + coenzyme A + H+
No genes
benzoyl-CoA + benzyl alcohol→benzyl benzoate + coenzyme A (EC 2.3.1.196)
No genes
benzyl benzoate + H2O→benzoate + benzyl alcohol + H+
No genes
Benzoate--CoA ligase:
benzoate + ATP + coenzyme A→benzoyl-CoA + AMP + diphosphate (EC 6.2.1.25)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information