MetaCyc Pathway: superpathway of purine nucleotide salvage in Pseudomonas fluorescens FW300-N2E3

Add experiment(s):


Adenosine kinase:
adenosine + ATP→AMP + ADP + H+
(EC 2.7.1.20)
No genes
Purine-nucleoside phosphorylase:
adenosine + phosphate→adenine + α-D-ribose-1-phosphate
(EC 2.4.2.1)
AO353_08525
AO353_14225
Adenylosuccinate synthase:
IMP + L-aspartate + GTP→adenylosuccinate + GDP + 2 H+ + phosphate
(EC 6.3.4.4)
AO353_13170
IMP dehydrogenase:
IMP + NAD+ + H2O→XMP + NADH + H+
(EC 1.1.1.205)
AO353_15950
AO353_25270
AO353_29360
Purine-nucleoside phosphorylase:
guanosine + phosphate→guanine + α-D-ribose-1-phosphate
(EC 2.4.2.1; 2.4.2.15)
AO353_08525
Adenine phosphoribosyltransferase (in reverse):
adenine + 5-phospho-α-D-ribose 1-diphosphate→AMP + diphosphate
(EC 2.4.2.7)
AO353_00665
Adenylosuccinate lyase:
adenylosuccinate→AMP + fumarate
(EC 4.3.2.2)
AO353_27715
GMP synthase (glutamine-hydrolyzing):
XMP + ATP + L-glutamine + H2O→GMP + AMP + L-glutamate + diphosphate + 2 H+
(EC 6.3.5.2)
AO353_10550
AO353_15955
Hypoxanthine phosphoribosyltransferase (in reverse):
guanine + 5-phospho-α-D-ribose 1-diphosphate→GMP + diphosphate
(EC 2.4.2.8)
AO353_00665
AO353_14860
Adenylate kinase:
AMP + ATP→2 ADP
(EC 2.7.4.3)
AO353_16315
Guanylate kinase:
GMP + ATP→GDP + ADP
(EC 2.7.4.8)
AO353_02935
AO353_09270
Ribonucleoside-diphosphate reductase (in reverse):
ADP + a reduced thioredoxin→dADP + an oxidized thioredoxin + H2O
(EC 1.17.4.1)
AO353_02840
AO353_03070
Nucleoside-diphosphate kinase:
GDP + ATP→GTP + ADP
(EC 2.7.4.6)
AO353_15870
AO353_16315
Nucleoside-diphosphate kinase:
dADP + ATP→ADP + dATP
(EC 2.7.4.6)
AO353_15870

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information