MetaCyc Pathway: 8-amino-7-oxononanoate biosynthesis IV in Pseudomonas fluorescens FW300-N2E3

Add experiment(s):


glutaryl-CoA + a malonyl-[acp] + H+→a 3-oxopimeloyl-[acp] + CO2 + coenzyme A
No genes
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxopimeloyl-[acp] + NADPH + H+→a (3R)-3-hydroxypimeloyl-[acp] + NADP+ (EC 1.1.1.100)
AO353_00945
AO353_01365
AO353_04045
AO353_11955
AO353_12610
AO353_13875
AO353_22325
AO353_23150
AO353_23170
AO353_24520
AO353_28590
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxypimeloyl-[acp]→a 2-enoyl-pimeloyl-[acp] + H2O (EC 4.2.1.59)
AO353_01755
AO353_16515
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a 2-enoyl-pimeloyl-[acp] + NADH + H+→a pimeloyl-[acp] + NAD+ (EC 1.3.1.9)
AO353_23455
AO353_27025
8-amino-7-oxononanoate synthase:
a pimeloyl-[acp] + L-alanine + H+→(8S)-8-amino-7-oxononanoate + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.47)
AO353_07520

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information