MetaCyc Pathway: folate polyglutamylation in Pseudomonas fluorescens FW300-N2E3

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Tetrahydrofolate synthase:
a tetrahydrofolate + ATP + L-glutamate→a tetrahydrofolate + ADP + phosphate (EC 6.3.2.17)
AO353_20675
Formate--tetrahydrofolate ligase:
a tetrahydrofolate + ATP + formate→an N10-formyltetrahydrofolate + ADP + phosphate (EC 6.3.4.3)
No genes
Glycine hydroxymethyltransferase:
a tetrahydrofolate + L-serine→a 5,10-methylenetetrahydrofolate + glycine + H2O (EC 2.1.2.1)
AO353_07665
AO353_10495
AO353_10530
AO353_14020
AO353_14025
AO353_29335
Tetrahydrofolate synthase:
an N10-formyltetrahydrofolate + ATP + L-glutamate→an N10-formyltetrahydrofolate + ADP + phosphate (EC 6.3.2.17)
AO353_20675
Tetrahydrofolate synthase:
a 5,10-methylenetetrahydrofolate + ATP + L-glutamate→a 5,10-methylenetetrahydrofolate + ADP + phosphate (EC 6.3.2.17)
AO353_20675

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information