MetaCyc Pathway: L-arginine degradation II (AST pathway) in Pseudomonas fluorescens FW300-N2E3

Arginine N-succinyltransferase:
L-arginine + succinyl-CoA→N²-succinyl-L-arginine + coenzyme A + H⁺ (EC 2.3.1.109)

N-succinylarginine dihydrolase:
N²-succinyl-L-arginine + 2 H⁺ + 2 H₂O→N²-succinyl-L-ornithine + 2 ammonium + CO₂ (EC 3.5.3.23)

AO353_03005

Succinylornithine transaminase:
N²-succinyl-L-ornithine + 2-oxoglutarate→N²-succinyl-L-glutamate 5-semialdehyde + L-glutamate (EC 2.6.1.81)

AO353_03025

Succinylglutamate-semialdehyde dehydrogenase:
N²-succinyl-L-glutamate 5-semialdehyde + NAD⁺ + H₂O→N²-succinylglutamate + NADH + 2 H⁺ (EC 1.2.1.71)

AO353_03010

Succinylglutamate desuccinylase:
N²-succinylglutamate + H₂O→L-glutamate + succinate (EC 3.5.1.96)

AO353_02995

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information