MetaCyc Pathway: L-tyrosine degradation I in Pseudomonas fluorescens FW300-N1B4

Add experiment(s):


Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
Pf1N1B4_1065
Pf1N1B4_160
Pf1N1B4_2018
Pf1N1B4_2139
Pf1N1B4_261
Pf1N1B4_27
Pf1N1B4_349
Pf1N1B4_3564
Pf1N1B4_3771
Pf1N1B4_386
Pf1N1B4_4186
Pf1N1B4_4425
Pf1N1B4_4646
Pf1N1B4_4672
Pf1N1B4_4996
Pf1N1B4_5070
Pf1N1B4_510
Pf1N1B4_5999
Pf1N1B4_818
Pf1N1B4_849
4-hydroxyphenylpyruvate dioxygenase:
3-(4-hydroxyphenyl)pyruvate + dioxygen→homogentisate + CO2 (EC 1.13.11.27)
Pf1N1B4_2747
Pf1N1B4_5003
Homogentisate 1,2-dioxygenase:
homogentisate + dioxygen→4-maleyl-acetoacetate + H+ (EC 1.13.11.5)
Pf1N1B4_1025
Maleylacetoacetate isomerase:
4-maleyl-acetoacetate→4-fumaryl-acetoacetate (EC 5.2.1.2)
Pf1N1B4_1023
Fumarylacetoacetase:
4-fumaryl-acetoacetate + H2O→acetoacetate + fumarate + H+ (EC 3.7.1.2)
Pf1N1B4_1024

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information