MetaCyc Pathway: superpathway of ornithine degradation in Pseudomonas fluorescens FW300-N1B4

Add experiment(s):


Ornithine decarboxylase:
L-ornithine + H+→putrescine + CO2 (EC 4.1.1.17)
Pf1N1B4_1136
Putrescine aminotransferase:
putrescine + 2-oxoglutarate→4-aminobutanal + L-glutamate (EC 2.6.1.82)
No genes
Glutamate--putrescine ligase:
putrescine + ATP + L-glutamate→γ-glutamyl-L-putrescine + ADP + H+ + phosphate (EC 6.3.1.11)
Pf1N1B4_2254
Pf1N1B4_4354
Aminobutyraldehyde dehydrogenase:
4-aminobutanal + NAD+ + H2O→4-aminobutanoate + NADH + 2 H+ (EC 1.2.1.19)
Pf1N1B4_171
Pf1N1B4_2132
Pf1N1B4_2673
Pf1N1B4_3024
Pf1N1B4_3029
Pf1N1B4_4244
Pf1N1B4_4264
Pf1N1B4_4355
Pf1N1B4_4502
Pf1N1B4_4920
Pf1N1B4_695
4-aminobutanal→1-pyrroline + H2O (spontaneous)
No genes
γ-glutamyl-L-putrescine + dioxygen + H2O→4-(γ-L-glutamylamino)butanal + ammonium + hydrogen peroxide (EC 1.4.3.M3)
Pf1N1B4_4356
Pf1N1B4_4824
Pf1N1B4_6047
4-(γ-L-glutamylamino)butanal + NAD(P)+ + H2O→4-(γ-L-glutamylamino)butanoate + NAD(P)H + 2 H+ (EC 1.2.1.99)
No genes
Gamma-glutamyl-gamma-aminobutyrate hydrolase:
4-(γ-L-glutamylamino)butanoate + H2O→4-aminobutanoate + L-glutamate (EC 3.5.1.94)
Pf1N1B4_2255
Pf1N1B4_4353

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information