MetaCyc Pathway: glycine cleavage in Pseudomonas fluorescens FW300-N1B4

a [glycine-cleavage complex H protein] N⁶-[(R)-lipoyl]-L-lysine + glycine + H⁺→a [glycine-cleavage complex H protein] N⁶-aminomethyldihydrolipoyl-L-lysine + CO₂ (EC 1.4.1.27; 1.4.4.2)

Pf1N1B4_2236

Pf1N1B4_621

a [glycine-cleavage complex H protein] N⁶-aminomethyldihydrolipoyl-L-lysine + a tetrahydrofolate→a [glycine-cleavage complex H protein] N⁶-dihydrolipoyl-L-lysine + ammonium + a 5,10-methylenetetrahydrofolate (EC 1.4.1.27; 2.1.2.10)

a [glycine-cleavage complex H protein] N⁶-dihydrolipoyl-L-lysine + NAD⁺→a [glycine-cleavage complex H protein] N⁶-[(R)-lipoyl]-L-lysine + NADH + H⁺ (EC 1.4.1.27; 1.8.1.4)

Pf1N1B4_1976

Pf1N1B4_3683

Pf1N1B4_4477

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information