MetaCyc Pathway: L-tyrosine degradation I in Pseudomonas stutzeri RCH2

Aspartate transaminase: L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)

Psest_1268

Psest_1295

Psest_1570

Psest_1710

Psest_1985

Psest_1990

Psest_3297

Psest_0779

4-hydroxyphenylpyruvate dioxygenase: 3-(4-hydroxyphenyl)pyruvate + dioxygen→homogentisate + CO2 (EC 1.13.11.27)

Psest_3514

Psest_4071

Homogentisate 1,2-dioxygenase: homogentisate + dioxygen→4-maleyl-acetoacetate + H+ (EC 1.13.11.5)

Psest_3513

Maleylacetoacetate isomerase: 4-maleyl-acetoacetate→4-fumaryl-acetoacetate (EC 5.2.1.2)

Psest_3511

Fumarylacetoacetase: 4-fumaryl-acetoacetate + H2O→acetoacetate + fumarate + H+ (EC 3.7.1.2)

Psest_3512

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information