MetaCyc Pathway: adipate biosynthesis in Pseudomonas stutzeri RCH2

Add experiment(s):


3-oxoadipyl-CoA thiolase:
acetyl-CoA + succinyl-CoA→3-oxoadipoyl-CoA + coenzyme A (EC 2.3.1.174)
Psest_3070
3-hydroxyacyl-CoA dehydrogenase (in reverse):
3-oxoadipoyl-CoA + NADH + H+→(3S)-hydroxyadipyl-CoA + NAD+ (EC 1.1.1.35)
Psest_2654
Psest_3109
Psest_3800
Psest_3969
Psest_4235
Enoyl-CoA hydratase:
(3S)-hydroxyadipyl-CoA→(2E)-5-carboxy-2-pentenoyl-CoA + H2O (EC 4.2.1.17)
Psest_2076
Psest_2437
Psest_2439
Psest_2654
Psest_2720
Psest_3109
Psest_3110
Psest_3800
Psest_3969
Psest_4235
(2E)-5-carboxy-2-pentenoyl-CoA + FADH2→adipoyl-CoA + FAD + H+
No genes
Succinate--CoA ligase (ADP-forming) (in reverse):
adipoyl-CoA + ADP + phosphate→adipate + ATP + coenzyme A (EC 6.2.1.5)
Psest_2490
Psest_2491

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information