MetaCyc Pathway: ketogenesis in Azospirillum brasilense Sp245

Add experiment(s):


Acetyl-CoA C-acyltransferase:
2 acetyl-CoA→acetoacetyl-CoA + coenzyme A (EC 2.3.1.16; 2.3.1.9)
AZOBR_RS20220
AZOBR_RS28180
AZOBR_RS30610
Hydroxymethylglutaryl-CoA synthase:
acetoacetyl-CoA + acetyl-CoA + H2O→(S)-3-hydroxy-3-methylglutaryl-CoA + coenzyme A + H+ (EC 2.3.3.10)
No genes
Hydroxymethylglutaryl-CoA lyase:
(S)-3-hydroxy-3-methylglutaryl-CoA→acetyl-CoA + acetoacetate (EC 4.1.3.4)
AZOBR_RS22280
AZOBR_RS25430
AZOBR_RS26360
3-hydroxybutyrate dehydrogenase (in reverse):
acetoacetate + NADH + H+→(R)-3-hydroxybutanoate + NAD+ (EC 1.1.1.30)
AZOBR_RS16640
AZOBR_RS27005
Acetoacetate decarboxylase:
acetoacetate + H+→acetone + CO2 (EC 4.1.1.4)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information