MetaCyc Pathway: 2-allylmalonyl-CoA biosynthesis in Azospirillum brasilense Sp245

Add experiment(s):


propanoyl-CoA + TcsB polyketide synthase→propanoyl-[TcsB polyketide synthase] + coenzyme A
No genes
malonyl-CoA + TcsA polyketide synthase→malonyl-[TcsA polyketide synthase] + coenzyme A
No genes
malonyl-[TcsA polyketide synthase] + propanoyl-[TcsB polyketide synthase] + H+→3-oxopentanoyl-[TcsA polyketide synthase] + CO2 + TcsB polyketide synthase
No genes
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
3-oxopentanoyl-[TcsA polyketide synthase] + NADPH + H+→(3R)-3-hydroxypentanoyl-[TcsA polyketide synthase] + NADP+ (EC 1.1.1.100)
AZOBR_RS04635
AZOBR_RS04695
AZOBR_RS05905
AZOBR_RS08305
AZOBR_RS08390
AZOBR_RS09155
AZOBR_RS09410
AZOBR_RS13310
AZOBR_RS16265
AZOBR_RS18775
AZOBR_RS21545
AZOBR_RS21600
AZOBR_RS22705
AZOBR_RS24695
AZOBR_RS25420
AZOBR_RS25730
AZOBR_RS25910
AZOBR_RS26450
AZOBR_RS27545
AZOBR_RS27580
AZOBR_RS27660
AZOBR_RS28175
AZOBR_RS29790
AZOBR_RS30020
AZOBR_RS31580
AZOBR_RS32755
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
(3R)-3-hydroxypentanoyl-[TcsA polyketide synthase]→(2E)-pent-2-enoyl-[TcsA polyketide synthase] + H2O (EC 4.2.1.59)
AZOBR_RS07370
(2E)-pent-2-enoyl-[TcsA polyketide synthase] + CO2 + NADPH→2-carboxypentanoyl-[TcsA polyketide synthase] + NADP+
No genes
2-carboxypentanoyl-[TcsA polyketide synthase] + FAD + H+→2-allylmalonyl-[TcsA polyketide synthase] + FADH2
No genes
2-allylmalonyl-[TcsA polyketide synthase] + coenzyme A→2-allylmalonyl-CoA + TcsA polyketide synthase
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information