MetaCyc Pathway: gondoate biosynthesis (anaerobic) in Azospirillum brasilense Sp245

Add experiment(s):


Beta-ketoacyl-acyl-carrier-protein synthase II:
an oleoyl-[acp] + a malonyl-[acp] + H+→an (11Z)-3-oxo-icos-11-enoyl-[acp] + a soluble [acyl-carrier protein] + CO2
(EC 2.3.1.179; 2.3.1.41)
AZOBR_RS04690
AZOBR_RS04705
AZOBR_RS08400
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
an (11Z)-3-oxo-icos-11-enoyl-[acp][cytosol] + NADPH[cytosol] + H+[cytosol]→a (3R,11Z)-3-hydroxy-icos-11-enoyl-[acp][cytosol] + NADP+[cytosol]
(EC 1.1.1.100)
AZOBR_RS04635
AZOBR_RS04695
AZOBR_RS05905
AZOBR_RS08305
AZOBR_RS08390
AZOBR_RS09155
AZOBR_RS09410
AZOBR_RS13310
AZOBR_RS16265
AZOBR_RS18775
AZOBR_RS21545
AZOBR_RS21600
AZOBR_RS22705
AZOBR_RS24695
AZOBR_RS25420
AZOBR_RS25730
AZOBR_RS25910
AZOBR_RS26450
AZOBR_RS27545
AZOBR_RS27580
AZOBR_RS27660
AZOBR_RS28175
AZOBR_RS29790
AZOBR_RS30020
AZOBR_RS31580
AZOBR_RS32755
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R,11Z)-3-hydroxy-icos-11-enoyl-[acp][cytosol]→a (2E,11Z)-icosa-2,11-dienoyl-[acp][cytosol] + H2O[cytosol]
(EC 4.2.1.59)
AZOBR_RS07370
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E,11Z)-icosa-2,11-dienoyl-[acp][cytosol] + NADH[cytosol] + H+[cytosol]→a gondoyl-[acp][cytosol] + NAD+[cytosol]
(EC 1.3.1.9)
AZOBR_RS08105
AZOBR_RS09570
AZOBR_RS10720
AZOBR_RS18895

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information